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IL-6 Receptor 抗体

IL6R 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7234279
发货至: 中国
  • 抗原 See all IL-6 Receptor (IL6R) 抗体
    IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
    适用
    人, 大鼠, 小鼠
    宿主
    • 46
    • 22
    • 5
    • 1
    • 1
    克隆类型
    • 49
    • 25
    • 1
    多克隆
    标记
    • 48
    • 13
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-6 Receptor antibody is un-conjugated
    应用范围
    • 50
    • 22
    • 22
    • 21
    • 12
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen Affinity Purification
    免疫原
    Recombinant Human Interleukin-6 receptor subunit alpha protein
    亚型
    IgG
  • 应用备注
    WB 1:1000-1:2000 IHC 1:100-1:300
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
    别名
    IL6R (IL6R 产品)
    别名
    IL6R antibody, il-6ra antibody, CD126 antibody, IL-6R-1 antibody, IL-6RA antibody, IL6Q antibody, IL6RA antibody, IL6RQ antibody, gp80 antibody, IL6R1 antibody, Il6ra antibody, IL-6Ralpha antibody, IL-6R antibody, Il6r antibody, interleukin 6 receptor antibody, interleukin 6 receptor, alpha antibody, IL6R antibody, il6r antibody, Il6r antibody, Il6ra antibody
    背景
    This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
    分子量

    Observed_MW: 80 kDa

    Calculated_MW: 40,51 kDa

    UniProt
    P08887
    途径
    JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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