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GCK 抗体

GCK 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7234072
发货至: 中国
  • 抗原 See all GCK 抗体
    GCK (Glucokinase (Hexokinase 4) (GCK))
    适用
    • 57
    • 27
    • 19
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 52
    • 9
    克隆类型
    • 55
    • 6
    多克隆
    标记
    • 37
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This GCK antibody is un-conjugated
    应用范围
    • 45
    • 25
    • 23
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen Affinity Purification
    免疫原
    Recombinant Mouse Glucokinase protein
    亚型
    IgG
    Top Product
    Discover our top product GCK Primary Antibody
  • 应用备注
    WB 1:1000-1:2000 IHC 1:100-1:200 IF 1:100-1:400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    GCK (Glucokinase (Hexokinase 4) (GCK))
    别名
    GCK (GCK 产品)
    别名
    FGQTL3 antibody, GK antibody, GLK antibody, HHF3 antibody, HK4 antibody, HKIV antibody, HXKP antibody, LGLK antibody, MODY2 antibody, Gk antibody, Gls006 antibody, GCK antibody, BA4487 antibody, glk antibody, hk4 antibody, hhf3 antibody, hkiv antibody, hxkp antibody, gck-A antibody, mody2 antibody, glucokinase antibody, GLUKA antibody, RNGK2 antibody, glucokinase antibody, glucokinase (hexokinase 4) L homeolog antibody, glucokinase (hexokinase 4) antibody, GCK antibody, Gck antibody, glcK antibody, Bphyt_1025 antibody, Halhy_6548 antibody, gk antibody, gck.L antibody, gck antibody
    背景
    Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
    分子量

    Observed_MW: 52 kDa

    Calculated_MW: 52 kDa

    UniProt
    P52792
    途径
    MAPK Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
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