KNSTRN 抗体
-
- 抗原 See all KNSTRN 抗体
- KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This KNSTRN antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant Human Small kinetochore-associated protein protein
- 亚型
- IgG
-
-
- 应用备注
- WB 1:500-1:2000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 2 mg/mL
- 缓冲液
- PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))
- 别名
- C15orf23 (KNSTRN 产品)
- 别名
- 1700025D04Rik antibody, C15orf23 antibody, D2Ertd750e antibody, SKAP antibody, Traf4af1 antibody, TRAF4AF1 antibody, kinetochore-localized astrin/SPAG5 binding antibody, kinetochore localized astrin/SPAG5 binding protein antibody, kinetochore-localized astrin/SPAG5 binding protein antibody, Knstrn antibody, KNSTRN antibody
- 背景
- Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase . Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division.
- 分子量
-
Observed_MW: 35 kDa
Calculated_MW: 35 kDa
- UniProt
- Q9Y448
- 途径
- M Phase
-