KIT 抗体 (AA 321-520)
-
- Key Features
-
- High quality KIT Primary Antibody for the detection of KIT.
- Reliable product with high standard validation data
- 抗原 See all KIT 抗体
- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
-
抗原表位
- AA 321-520
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This KIT antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- 原理
- Polyclonal Antibody to Stem Cell Factor Receptor (SCFR)
- 特异性
- The antibody is a rabbit polyclonal antibody raised against SCFR. It has been selected for its ability to recognize SCFR in immunohistochemical staining and western blotting.
- 纯化方法
- Antigen-specific affinity chromatography followed by Protein A affinity chromatography
- 免疫原
- Recombinant Stem Cell Factor Receptor (SCFR) corresdonding to Thr321~Pro520 (Accession # P10721) with N-terminal His Tag
- 亚型
- IgG
- Top Product
- Discover our top product KIT Primary Antibody
- Product Specific Information
-
- What can the KIT Antibody ABIN7431107 be used for?
- This polyclonal KIT Antibody detects KIT. The KIT Antibody has been validated for various applications and can be used for the detection of KIT and derivatives by Western Blotting, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry.
- What validation data is available for this KIT Antibody?
- The Primary Antibody has currently 6 product images that show its performance in a variety of applications. The product is currently available in 1 mL, 20 μL, 100 μL, 200 μL quantities. KIT Antibody for the detection of KIT and derivatives.
- What is the function of KIT?
- This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
-
-
- 应用备注
-
Western blotting: 0.5-2 μg/mL
Immunohistochemistry: 5-20 μg/mL
Immunocytochemistry: 5-20 μg/mL
Optimal working dilutions must be determined by end user.
- 说明
-
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
- 有效期
- 24 months
-
- 抗原
- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
- 别名
- Stem Cell Factor Receptor (KIT 产品)
- 别名
- C-Kit antibody, CD117 antibody, PBT antibody, SCFR antibody, Bs antibody, Fdc antibody, Gsfsco1 antibody, Gsfsco5 antibody, Gsfsow3 antibody, SCO1 antibody, SCO5 antibody, SOW3 antibody, Ssm antibody, Tr-kit antibody, W antibody, c-KIT antibody, c-kit antibody, MGF antibody, KIT antibody, C-KIT antibody, kit antibody, receptor antibody, sparse antibody, Xkl-1 antibody, kit-a antibody, kit-b antibody, kl1-A antibody, krk1 antibody, pbt antibody, scfr antibody, KIT proto-oncogene receptor tyrosine kinase antibody, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a antibody, KIT proto-oncogene receptor tyrosine kinase S homeolog antibody, KIT antibody, Kit antibody, kita antibody, kit antibody, kit.S antibody
- 背景
- CD117, KIT, C-Kit, PBT, p145 c-Kit, C-Kit Receptor, Tyrosine-Protein Kinase, V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog, Piebald Trait
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
-