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SARS-CoV-2 Spike S1 抗体 (RBD)

适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA 宿主: Llama Monoclonal T4P3-B5 unconjugated single-domain Antibody (sdAb)
产品编号 ABIN6992312
发货至: 中国
  • 抗原 See all SARS-CoV-2 Spike S1 抗体
    SARS-CoV-2 Spike S1
    片段
    single-domain Antibody (sdAb)
    抗原表位
    • 12
    • 3
    • 2
    • 2
    • 1
    RBD
    适用
    • 40
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    SARS Coronavirus-2 (SARS-CoV-2)
    宿主
    • 16
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Llama
    克隆类型
    • 27
    • 9
    • 5
    单克隆
    标记
    • 35
    • 3
    • 1
    • 1
    • 1
    This SARS-CoV-2 Spike S1 antibody is un-conjugated
    应用范围
    • 40
    • 9
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    纯化方法
    SARS-CoV-2 (COVID-19) S1 RBD Antibody [T4P3-B5] is affinity chromatography purified via Nickel column. Antibody is supplied as a His-tagged purified protein.  It also contains a myc-tag for detection.
    免疫原
    SARS-CoV-2 S protein RBD containing C-terminal His Tag. The protein was expressed in human 293 cells (HEK293). It contains amino acids Arg 319 - Lys 537.
    克隆位点
    T4P3-B5
    Top Product
    Discover our top product SARS-CoV-2 Spike S1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    SARS-CoV-2 (COVID-19) S1 RBD Antibody [T4P3-B5] Antibody is supplied in PBS.
    储存条件
    -20 °C
    储存方法
    SARS-CoV-2 (COVID-19) S1 RBD antibody should be stored in working aliquots at -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    SARS-CoV-2 Spike S1
    别名
    SARS-CoV-2 S1 (SARS-CoV-2 Spike S1 产品)
    别名
    E2 antibody, Surface Glycoprotein antibody, S antibody
    物质类
    Viral Protein
    背景
    Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection (3). The spike protein is the major target for neutralizing antibodies and vaccine development (4). The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19 (5). The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein (6).
    基因ID
    43740568
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