SARS-CoV-2 ORF7a 抗体
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA, IHC
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all SARS-CoV-2 ORF7a products
- SARS-CoV-2 ORF7a
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适用
- SARS Coronavirus-2 (SARS-CoV-2)
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SARS-CoV-2 ORF7a antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 纯化方法
- SARS-CoV-2 (COVID-19) ORF7a Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Anti-SARS-CoV-2 (COVID-19) ORF7a antibody was raised against a peptide corresponding to 15 amino acids near the central domain of SARS-CoV-2 (COVID-19) ORF7a protein. The immunogen is located within 40-90 amino acids of the SARS-CoV-2 (COVID-19) ORF7a protein.
- 亚型
- IgG
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anti-SARS-CoV-2 ORF7a antibody
适用: SARS Coronavirus-2 (SARS-CoV-2) WB 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- IHC: 1 μ,g/mL Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) ORF7a antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA. All other applications and species not yet tested.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- SARS-CoV-2 (COVID-19) ORF7a antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- SARS-CoV-2 (COVID-19) ORF7a antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- SARS-CoV-2 ORF7a
- Abstract
- SARS-CoV-2 ORF7a 产品
- 别名
- ORF7a protein antibody, ORF7a antibody
- 物质类
- Viral Protein
- 背景
- Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). SARS-CoV-2 virus proteins include structural proteins, non-structural proteins and accessory factors. The structure of SARS-CoV-2 consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. SARS-CoV-2 non-structural protein is ORF1ab that consists of 16 proteins (nsp1-nsp16), while accessory factors include ORF3a, ORF3b, ORF6, ORF7a, ORF7b, ORF8, ORF9b, ORF7a and ORF7a. ORF7a plays a role as antagonist of host tetherin (BST2), disrupting its antiviral effect. It acts by binding to BST2 thereby interfering with its glycosylation. It may suppress small interfering RNA (siRNA) and may bind to host ITGAL, thereby playing a role in attachment or modulation of leukocytes (3).
- 分子量
- 14kD kDa
- 基因ID
- 43740573
- UniProt
- P0DTC7
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