ELISA, Western Blotting (WB), Immunocytochemistry (ICC)
特异性
SUSD3 antibody is human and mouse reactive. Multiple isoforms of SUSD3 are known to exist.
纯化方法
SUSD3 Antibody is affinity chromatography purified via peptide column.
免疫原
SUSD3 antibody was raised against a 16 amino acid peptide from near the center of human SUSD3. The immunogen is located within amino acids 120 - 170 of SUSD3.
SUSD3 antibody can be used for the detection of SUSD3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
SUSD3 Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
SUSD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Little is known of the function of the sushi domain containing 3 protein (SUSD3), but its expression has been reported in estrogen receptor-alpha (ERalpha)-positive breast tumors with decreased expression reported in aggressive malignant tumors (1,2). Recently, SUSD3 has been found to promote estrogen-dependent cell proliferation and may regulate cell-cell and cell-substrate interactions and migration in breast cancer (3). Furthermore, elevated SUSD3 mRNA levels were observed in aromatase inhibitor-responsive breast tumors, suggesting that it may also serve as a novel predictor of response to endocrine therapy and a potential therapeutic target (3).