Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
特异性
PALMD antibody is human specific. At least two isoforms are known to exist.
纯化方法
PALMD antibody is affinity chromatography purified via peptide column.
免疫原
PALMD antibody was raised against a 15 amino acid peptide near the carboxy terminus of human PALMD. The immunogen is located within amino acids 460 - 510 of PALMD.
PALMD antibody can be used for detection of PALMD by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
PALMD antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
PALMD antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Palmdelphin (PALMD) is a member of the paralemmin families that are lipid-anchored proteins having a role in the cell shape control and cell dynamics (1,2). While Paralemmin proteins typically anchor to the cytoplasm through via palmytoylation and prenylation, PALMD is found predominantly in the cytosol (3). PALMD is targeted to the nucleus to induce apoptosis in response to DNA damage (3-5). Abnormal genetic alterations in PALMD are observed in many malignant tumors (5).