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ARID1A 抗体 (N-Term)

ARID1A 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6992134
发货至: 中国
  • 抗原 See all ARID1A 抗体
    ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
    抗原表位
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 580-630, N-Term
    适用
    • 33
    • 18
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 30
    • 3
    克隆类型
    • 23
    • 10
    多克隆
    标记
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This ARID1A antibody is un-conjugated
    应用范围
    • 12
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    ARID1A antibody is human, mouse and rat reactive. Multiple isoforms of ARID1A protein are known to exist.
    纯化方法
    ARID1A antibody is affinity chromatography purified via peptide column.
    免疫原
    ARID1A antibody was raised against an 18 amino acid peptide near the amino terminus of human ARID1A. The immunogen is located within amino acids 580 - 630 of ARID1A.
    亚型
    IgG
    Top Product
    Discover our top product ARID1A Primary Antibody
  • 应用备注
    ARID1A antibody can be used for detection of ARID1A by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    ARID1A antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    ARID1A antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原
    ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
    别名
    ARID1A (ARID1A 产品)
    别名
    B120 antibody, BAF250 antibody, BAF250a antibody, BM029 antibody, C1orf4 antibody, ELD antibody, MRD14 antibody, OSA1 antibody, P270 antibody, SMARCF1 antibody, hELD antibody, hOSA1 antibody, 1110030E03Rik antibody, Osa1 antibody, Smarcf1 antibody, ARID1A antibody, wu:fb79b07 antibody, wu:fb95g08 antibody, zgc:171438 antibody, AT-rich interaction domain 1A antibody, AT rich interactive domain 1A (SWI-like) antibody, AT rich interactive domain 1Aa (SWI-like) antibody, ARID1A antibody, Arid1a antibody, arid1a antibody, arid1aa antibody
    背景
    The ARID1A protein is a member of the SWI/SNF family, whose members are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. ARID1A is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin (1). It possesses a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. The C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that ARID1A confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions (2).
    分子量
    Predicted: 133, 227, 251 kDa

    Observed: 130, 260 kDa
    基因ID
    8289
    NCBI登录号
    NP_006006
    UniProt
    O14497
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation
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