Western Blotting (WB), ELISA, Immunofluorescence (IF)
特异性
MKRN3 antibody is human specific. MKRN3 antibody is predicted to not cross-react with other members of the MKRN protein family.
纯化方法
MKRN3 antibody is affinity chromatography purified via peptide column.
免疫原
MKRN3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human MKRN3. The immunogen is located within amino acids 400 - 450 of MKRN3.
CPPB2 antibody, D15S9 antibody, RNF63 antibody, ZFP127 antibody, ZNF127 antibody, D7H15S9-1 antibody, Zfp127 antibody, makorin ring finger protein 3 antibody, makorin, ring finger protein, 3 antibody, MKRN3 antibody, Mkrn3 antibody
背景
The Makorin ring finger 3 (MKRN3) protein contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. The MKRN3 gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome (1), but a deletion of the gene does not (2). A deficiency of MKRN3 has been shown to cause central precocious puberty in humans (3).