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SARS-CoV-2 Spike S1 抗体

适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6992075
发货至: 中国
  • 抗原 See all SARS-CoV-2 Spike S1 抗体
    SARS-CoV-2 Spike S1
    适用
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    SARS Coronavirus-2 (SARS-CoV-2)
    宿主
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    克隆类型
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    多克隆
    标记
    • 35
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    This SARS-CoV-2 Spike S1 antibody is un-conjugated
    应用范围
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    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
    纯化方法
    SARS-CoV-2 (COVID-19) Spike S1 antibody is affinity chromatography purified via peptide column.
    免疫原
    Anti-SARS-CoV-2 (COVID-19) Spike S1 antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of SARS-CoV-2 (COVID-19) Spike S1 glycoprotein. The immunogen is located within the first 50 amino acids of SARS-CoV-2 (COVID-19) Spike S1 protein.
    亚型
    IgG
    Top Product
    Discover our top product SARS-CoV-2 Spike S1 Primary Antibody
  • 应用备注
    IHC: 0.5 μ,g/mL, WB: 1 μ,g/mL, IF: 5 μ,g/mL,

    Antibody validated: Western Blot in human samples, Immunofluorescence in human samples, Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) Spike S1 antibody can be used for the detection of SARS-CoV-2 (COVID-19) Spike protein in ELISA. It will detect 4 ng of free peptide at 1 μ,g/mL. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    SARS-CoV-2 (COVID-19) Spike S1 antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    SARS-CoV-2 (COVID-19) Spike S1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    SARS-CoV-2 Spike S1
    Abstract
    SARS-CoV-2 Spike S1 产品
    别名
    E2 antibody, Surface Glycoprotein antibody, S antibody
    物质类
    Viral Protein
    背景
    Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection (3). The spike protein is the major target for neutralizing antibodies and vaccine development (4). The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19 (5). The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein (6).
    基因ID
    43740568
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