SKI2W antibody is human, mouse and rat reactive. At least two isoforms of SKI2W are known to exist, this antibody will detect both isoforms.
纯化方法
SKI2W antibody is affinity chromatography purified via peptide column.
免疫原
SKI2W antibody was raised against a 16 amino acid peptide near the amino terminus of human SKI2W. The immunogen is located within amino acids 60 - 110 of SKI2W.
SKI2W antibody can be used for detection of SKI2W by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
SKI2W antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
SKI2W antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
SKI2W (SKIV2L, Helicase-like protein), a DEVH-box protein, is a component of the SKI complex which is involved in the regulation of translation and RNA turnover (1,2). SKI2W is a nucleolar and cytoplasmic protein that has a putative RNA helicase domain (2). The potential roles of Ski2W on the clearance of degraded nuclear and cytoplasmic RNA raised their possibilities as susceptibility genes of systemic lupus erythematosus (3,4).