ATM Interactor 抗体 (N-Term)
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- 抗原 See all ATM Interactor (ATMIN) 抗体
- ATM Interactor (ATMIN)
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抗原表位
- AA 200-250, N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATM Interactor antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- ATMIN antibody is human, mouse and rat reactive. At least three isoforms of ATMIN are known to exist.
- 纯化方法
- ATMIN antibody is affinity chromatography purified via peptide column.
- 免疫原
- ATMIN antibody was raised against a 19 amino acid peptide near the amino terminus of human ATMIN. The immunogen is located within amino acids 200 - 250 of ATMIN.
- 亚型
- IgG
- Top Product
- Discover our top product ATMIN Primary Antibody
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- 应用备注
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ATMIN antibody can be used for detection of ATMIN by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry at 5 μ,g/mL. For Immunoflorescence start at 2.5 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- ATMIN Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- ATMIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- ATM Interactor (ATMIN)
- 别名
- ATMIN (ATMIN 产品)
- 别名
- Asciz antibody, mKIAA0431 antibody, RGD1305781 antibody, ASCIZ antibody, ZNF822 antibody, ATM interactor antibody, ATM interactor L homeolog antibody, Atmin antibody, ATMIN antibody, atmin.L antibody, atmin antibody
- 背景
- The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51 (1). ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects (2). It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL1 expression (3).
- 分子量
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Predicted: 73, 79, 91 kDa
Observed: 72 kDa - 基因ID
- 23300
- NCBI登录号
- NP_056066
- UniProt
- O43313
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