ELISA, Western Blotting (WB), Immunofluorescence (IF)
特异性
GLIPR1 antibody is human and mouse reactive. At least two isoforms of GLIPR1 are known to exist, this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins.
纯化方法
GLIPR1 antibody is affinity chromatography purified via peptide column.
免疫原
GLIPR1 antibody was raised against an 18 amino acid peptide near the center of human GLIPR1. The immunogen is located within amino acids 60 - 110 of GLIPR1.
CRISP7 antibody, GLIPR antibody, RTVP1 antibody, 2410114O14Rik antibody, RTVP-1 antibody, mRTVP-1 antibody, GLIPR1 antibody, zgc:65887 antibody, GLI pathogenesis related 1 antibody, GLI pathogenesis-related 1 antibody, GLI pathogenesis-related 1 (glioma) antibody, GLI pathogenesis-related 1b antibody, GLIPR1 antibody, Glipr1 antibody, glipr1b antibody
背景
The glioma pathogensis-related protein 1 (GLIPR1) is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (1). GLIPR1 is a tumor suppressor whose expression is regulated by p53, its increased expression is associated with myelomocytic differentiation in macrophages, whereas decreased expression of this gene through gene methylation is associated with prostate cancer (2). The GLIPR1 gene is part of a p53 target gene cluster that includes GLIPR1L1 and GLIPR1L2, two highly homologous proteins whose expression patterns vary (3).