IL-37 抗体 (N-Term)
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- 抗原 See all IL-37 (IL37) 抗体
- IL-37 (IL37) (Interleukin 37 (IL37))
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抗原表位
- AA 30-80, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL-37 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- IL-37 antibody is human specific. Multiple isoforms of IL-37 are known to exist, this antibody will only detect the largest isoform. IL-37 antibody is predicted to not cross-react with IL-36.
- 纯化方法
- IL-37 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- IL-37 antibody was raised against a 17 amino acid peptide near the amino terminus of human IL-37. The immunogen is located within amino acids 30 - 80 of IL-37 .
- 亚型
- IgG
- Top Product
- Discover our top product IL37 Primary Antibody
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anti-Interleukin 37 (IL37) antibody
IL37 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 37 (IL37) (AA 1-218) antibodyIL37 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6A6 unconjugated
anti-Interleukin 37 (IL37) (AA 1-218) antibodyIL37 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 37 (IL37) (AA 46-218) antibodyIL37 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 37 (IL37) (AA 27-192) antibodyIL37 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 1# unconjugated
anti-Interleukin 37 (IL37) (AA 1-218) antibodyIL37 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 37 (IL37) (AA 27-192) antibodyIL37 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IL-37 antibody can be used for detection of IL-37 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- IL-37 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- IL-37 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- IL-37 (IL37) (Interleukin 37 (IL37))
- 别名
- IL-37 (IL37 产品)
- 别名
- FIL1 antibody, FIL1(ZETA) antibody, FIL1Z antibody, IL-1F7 antibody, IL-1H antibody, IL-1H4 antibody, IL-1RP1 antibody, IL-37 antibody, IL1F7 antibody, IL1H4 antibody, IL1RP1 antibody, interleukin 37 antibody, IL37 antibody
- 背景
- Interleukin 37 (IL-37) is a member of the interleukin 1 cytokine family (reviewed in 1). It can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). IL-37 also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18 (1). IL-37 can also interact with Smad3 and expression of IL-37 in macrophages or epithelial cells resulted in near complete suppression of pro-inflammatory cytokines, suggesting that IL-37 may act as a natural suppressor of the innate inflammatory and immune responses (2,3).
- 分子量
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Predicted: 24 kDa
Observed: 23kDa - 基因ID
- 27178
- NCBI登录号
- NP_055254
- UniProt
- Q9NZH6
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