CISD2 抗体 (AA 40-90)
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- 抗原 See all CISD2 抗体
- CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))
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抗原表位
- AA 40-90
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CISD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- CISD2 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- CISD2 antibody was raised against a 15 amino acid peptide near the center of human CISD2. The immunogen is located within amino acids 40 - 90 of CISD2.
- 亚型
- IgG
- Top Product
- Discover our top product CISD2 Primary Antibody
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anti-CDGSH Iron Sulfur Domain 2 (CISD2) (AA 61-135) antibody
CISD2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CDGSH Iron Sulfur Domain 2 (CISD2) (AA 110-144) antibodyCISD2 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51992 unconjugated
anti-CDGSH Iron Sulfur Domain 2 (CISD2) (N-Term) antibodyCISD2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-CDGSH Iron Sulfur Domain 2 (CISD2) (N-Term) antibodyCISD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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CISD2 antibody was raised against a 15 amino acid peptide near the center of human CISD2.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- CISD2 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- CISD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))
- 别名
- CISD2 (CISD2 产品)
- 别名
- ERIS antibody, Miner1 antibody, NAF-1 antibody, WFS2 antibody, ZCD2 antibody, 1500009M05Rik antibody, 1500026J14Rik antibody, 1500031D15Rik antibody, AI848398 antibody, B630006A20Rik antibody, Noxp70 antibody, Zcd2 antibody, RGD1566242 antibody, zgc:64148 antibody, eris antibody, miner1 antibody, wfs2 antibody, zcd2 antibody, cisd2 antibody, BcDNA:RE49709 antibody, Dmel\\CG1458 antibody, CDGSH iron sulfur domain 2 antibody, CDGSH iron sulfur domain 2 L homeolog antibody, CDGSH iron sulfur domain 2 S homeolog antibody, CISD2 antibody, Cisd2 antibody, cisd2 antibody, cisd2.L antibody, cisd2.S antibody
- 背景
- CISD2 Antibody: Defects in the CISD2 (CDGSH iron sulfur domain 2) gene are a cause of the neurodegenerative disorder Wolfram syndrome 2. CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum and mitochondria and binds an iron/sulfur cluster. CISD2 interacts with Bcl-2 and can be displaced by the BH3-only protein BIK and contributes to the regulation of BIK-initiated autophagy. CISD2 deficiency in mice causes mitochondrial breakdown accompanied by autophagic cell death as well as the development of premature aging phenotype.
- 分子量
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Predicted: 15 kDa
Observed: 15 kDa - 基因ID
- 493856
- NCBI登录号
- NP_001008389
- UniProt
- Q8N5K1
- 途径
- Activation of Innate immune Response
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