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WAC 抗体 (AA 210-260)

WAC 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991845
发货至: 中国
  • 抗原 See all WAC 抗体
    WAC (WW Domain Containing Adaptor with Coiled-Coil (WAC))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 210-260
    适用
    人, 小鼠, 大鼠
    宿主
    • 22
    克隆类型
    • 22
    多克隆
    标记
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    This WAC antibody is un-conjugated
    应用范围
    • 17
    • 17
    • 13
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    At least two isoforms of WAC are known to exist, this antibody will detect the larger isoform.
    纯化方法
    WAC Antibody is affinity chromatography purified via peptide column.
    免疫原
    WAC antibody was raised against a 19 amino acid peptide near the center of human WAC . The immunogen is located within amino acids 210 - 260 of WAC.
    亚型
    IgG
    Top Product
    Discover our top product WAC Primary Antibody
  • 应用备注
    WAC Antibody can be used for detection of WAC by Western blot at 1 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    WAC Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    WAC antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原
    WAC (WW Domain Containing Adaptor with Coiled-Coil (WAC))
    别名
    WAC (WAC 产品)
    别名
    BM-016 antibody, PRO1741 antibody, Wwp4 antibody, 1110067P07Rik antibody, A230035H12Rik antibody, AI256735 antibody, AI256776 antibody, DKFZp468H162 antibody, wac antibody, wu:fc13f04 antibody, wu:fj68f01 antibody, zgc:55755 antibody, RGD1562407 antibody, zgc:101828 antibody, WW domain containing adaptor with coiled-coil antibody, WW domain containing adaptor with coiled-coil a antibody, WW domain containing adaptor with coiled-coil b antibody, WAC antibody, Wac antibody, wac antibody, waca antibody, wacb antibody
    背景
    WAC Antibody: The WW domain containing adaptor with coiled-coil protein (WAC) contains a WW domain that mediates protein-protein interactions and colocalizes with RNA splicing factor SC35. Further studies have indicated that WAC is a functional partner of the RNF20/40 complex that ubiquitinates Histone H2B, and that WAC regulates H2B ubiquitination. WAC targets RNF20/40 to associate with RNA polymerase II complex for H2B ubiquitination at active transcription sites. WAC-dependent transcription is also important for cell-cycle checkpoint activation in response to genotoxic stress.
    分子量
    Predicted: 71 kDa

    Observed: 75 kDa
    基因ID
    51322
    NCBI登录号
    NP_057712
    UniProt
    Q9BTA9
    途径
    Chromatin Binding
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