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PLA1A 抗体 (C-Term)

PLA1A 适用: 人, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991764
发货至: 中国
  • 抗原 See all PLA1A 抗体
    PLA1A (Phospholipase A1 Member A (PLA1A))
    抗原表位
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 380-430, C-Term
    适用
    • 35
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 31
    • 4
    克隆类型
    • 34
    • 1
    多克隆
    标记
    • 18
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PLA1A antibody is un-conjugated
    应用范围
    • 24
    • 16
    • 13
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    特异性
    At least three isoforms of PLA1A are known to exist, this antibody will detect all three isoforms.
    纯化方法
    PLA1A Antibody is affinity chromatography purified via peptide column.
    免疫原
    PLA1A antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human PLA1A. The immunogen is located within amino acids 380 - 430 of PLA1A.
    亚型
    IgG
    Top Product
    Discover our top product PLA1A Primary Antibody
  • 应用备注
    PLA1A antibody can be used for detection of PLA1A by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PLA1A Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    PLA1A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    PLA1A (Phospholipase A1 Member A (PLA1A))
    别名
    PLA1A (PLA1A 产品)
    别名
    PS-PLA1 antibody, PSPLA1 antibody, AA986889 antibody, Ps-pla1 antibody, Pspla1 antibody, wu:fi26h09 antibody, zgc:77160 antibody, AH antibody, ARWH2 antibody, LAH2 antibody, LPDLR antibody, PLA1B antibody, mPA-PLA1 antibody, phospholipase A1 member A antibody, lipase H antibody, PLA1A antibody, Pla1a antibody, pla1a antibody, CpipJ_CPIJ002492 antibody, CpipJ_CPIJ007883 antibody, LIPH antibody
    背景
    PLA1A Antibody: PLA1A is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine (PS) in liposomes and can also hydrolyze PS in apoptotic cells and activate platelets where the resulting 2-acyl-lysophosphatidylserine acts as a lipid mediator for mast cells, T cells, and neural cells, suggesting that a major function of PLA1A may be the production of lysophospholipid mediators. PLA1A is upregulated in rat peripheral blood cells bearing long-term surviving cardiac allograft. PLA1A is also expressed in human THP-1-derived macrophages and this expression is upregulated in cells treated with lipopolysaccharide, a TLR4 ligand. This upregulation is inhibited with corticosteroids, which are often used at high dosages to suppress chronic allograft rejection.
    分子量
    50 kDa
    基因ID
    51365
    NCBI登录号
    NP_056984
    UniProt
    Q53H76
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