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KCP 抗体 (C-Term)

KCP 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991728
发货至: 中国
  • 抗原 See all KCP 抗体
    KCP (Kielin/Chordin-Like Protein (KCP))
    抗原表位
    AA 1320-1370, C-Term
    适用
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 2
    克隆类型
    • 2
    多克隆
    标记
    • 2
    This KCP antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA
    特异性
    At least two isoforms of CRIM2 are known to exist, this antibody will only detect the larger isoform. CRIM2 antibody is predicted to not cross-react with CRIM1.
    纯化方法
    CRIM2 Antibody is affinity chromatography purified via peptide column.
    免疫原
    CRIM2 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human CRIM2. The immunogen is located within amino acids 1320 - 1370 of CRIM2.
    亚型
    IgG
  • 应用备注
    CRIM2 antibody can be used for detection of CRIM2 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    CRIM2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    CRIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    KCP (Kielin/Chordin-Like Protein (KCP))
    别名
    CRIM2 (KCP 产品)
    别名
    CRIM2 antibody, KCP1 antibody, NET67 antibody, AW060220 antibody, CRIM-2 antibody, Crim2 antibody, Gm793 antibody, KCP-1 antibody, RGD1561119 antibody, crim2 antibody, kielin/chordin-like protein antibody, kielin/chordin-like protein L homeolog antibody, KCP antibody, LOC515624 antibody, Kcp antibody, kcp.L antibody
    背景
    CRIM2 Antibody: CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-β,1, suppressing activin- and TGF-β,1-dependent transcription.
    基因ID
    375616
    NCBI登录号
    NP_001129386
    UniProt
    Q6ZWJ8
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