ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
特异性
GBP6 antibody is predicted to not cross-react with other GBP family members.
纯化方法
GBP6 Antibody is affinity chromatography purified via peptide column.
免疫原
GBP6 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human GBP6. The immunogen is located within the last 50 amino acids of GBP6.
GBP6 antibody can be used for detection of GBP6 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
GBP6 Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
GBP6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
AI595338 antibody, Mpa2l antibody, guanylate binding protein 6 antibody, guanylate binding protein family member 6 antibody, Gbp6 antibody, GBP6 antibody
背景
GBP6 Antibody: The guanylate-binding proteins (GBPs), a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN) (1,3). GBP6 is induced by IFN and hydrolyzes GTP to both GDP and GMP. The precise function of GBP6 is still under investigation.