LY6K Antibody is affinity chromatography purified via peptide column.
免疫原
LY6K antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human LY6K. The immunogen is located within the first 50 amino acids of LY6K.
LY6K antibody can be used for detection of LY6K by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
LY6K Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
LY6K antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原
Ly6k
(Lymphocyte Antigen 6 Complex, Locus K (Ly6k))
LY6K antibody, CT97 antibody, HSJ001348 antibody, ly-6K antibody, 2410015A16Rik antibody, 3110035B01Rik antibody, mLy-6K antibody, lymphocyte antigen 6 family member K antibody, lymphocyte antigen 6 complex, locus K antibody, LY6K antibody, Ly6k antibody
背景
LY6K Antibody: The lymphocyte antigen 6 complex locus K (LY6K), a member of cancer-testis antigen was initially identified as a molecular marker for head-and-neck squamous cell carcinoma as well a breast cancer. LY6K is a GPI-anchored membrane protein that is specifically associated with germ cell marker TEX101 and is strongly observed in testis, but only weakly in other tissues. LY6K mRNA was found to be upregulated in numerous bladder cancers due to gene amplification. Furthermore, knockdown experiments using LY6K siRNA reduced cell growth, migration and invasion in bladder carcinoma cell lines, suggesting that LY6K contributes to bladder cancer development.