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CMYA5 抗体 (C-Term)

CMYA5 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991554
发货至: 中国
  • 抗原 See all CMYA5 products
    CMYA5 (Cardiomyopathy Associated 5 (CMYA5))
    抗原表位
    AA 3810-3860, C-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 1
    克隆类型
    • 1
    多克隆
    标记
    • 1
    This CMYA5 antibody is un-conjugated
    应用范围
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    SPRYD2 antibody is predicted to not cross-react with other SPRYD protein family members. At least four isoforms of SPRYD2 are known to exist.
    纯化方法
    SPRYD2 Antibody is affinity chromatography purified via peptide column.
    免疫原
    SPRYD2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SPRYD2. The immunogen is located within amino acids 3810 - 3860 of SPRYD2.
    亚型
    IgG
  • 应用备注
    SPRYD2 antibody can be used for detection of SPRYD2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    SPRYD2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    SPRYD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    CMYA5 (Cardiomyopathy Associated 5 (CMYA5))
    别名
    SPRYD2 (CMYA5 产品)
    别名
    cmya5l antibody, DKFZp469P2126 antibody, C5orf10 antibody, SPRYD2 antibody, TRIM76 antibody, 2310076E16Rik antibody, 2310076E21Rik antibody, AA420382 antibody, AI504003 antibody, Srfsd antibody, Tims antibody, sr553 antibody, cardiomyopathy associated 5 antibody, CMYA5 antibody, cmya5 antibody, Cmya5 antibody
    背景
    SPRYD2 Antibody: SPRYD2, also known as Myospryn, was originally identified as the muscle-specific partner of dysbindin and as a Mef-2 target gene. It is a large scaffolding protein localized to the Z-disc/costamere region of striated muscle. SPRYD2 includes a noncanonical tripartite motif (TRIM-like) that lacks the RING domain but consists of a B-box coiled coil (BBC), fibronectin 3 (FN3) repeats, and SPRY domains. SPRYD2 interacts with desmin and calcineurin, and it has been suggested to play a role in the biogenesis of lysosome and negatively regulates slow-fiber-type transformation and skeletal muscle regeneration. SPRYD2 is dysregulated in Duchenne muscular dystrophy.
    基因ID
    202333
    NCBI登录号
    NP_705838
    UniProt
    Q8N3K9
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