BCL9L 抗体 (N-Term)
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- 抗原 See all BCL9L 抗体
- BCL9L (B-Cell CLL/lymphoma 9-Like (BCL9L))
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抗原表位
- AA 20-70, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BCL9L antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- Bcl9L antibody is predicted to not cross-react with other Bcl family members. At least four isoforms of Bcl9L are known to exist, this antibody will detect all four.
- 纯化方法
- Bcl9L Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Bcl9L antibody was raised against a 20 amino acid synthetic peptide near the amino terminus of human Bcl9L. The immunogen is located within amino acids 20 - 70 of Bcl9L.
- 亚型
- IgG
- Top Product
- Discover our top product BCL9L Primary Antibody
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anti-B-Cell CLL/lymphoma 9-Like (BCL9L) (AA 606-751) antibody
BCL9L 适用: 人 WB, ELISA, ICC, FACS, IHC, Neut 宿主: 小鼠 Monoclonal 1C9G2 unconjugated
anti-B-Cell CLL/lymphoma 9-Like (BCL9L) (AA 147-176), (N-Term) antibodyBCL9L 适用: 人 WB 宿主: 兔 Polyclonal RB41624 unconjugated
anti-B-Cell CLL/lymphoma 9-Like (BCL9L) (N-Term) antibodyBCL9L 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Bcl9L antibody can be used for detection of Bcl9L by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL and immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Bcl9L Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- Bcl9L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- BCL9L (B-Cell CLL/lymphoma 9-Like (BCL9L))
- 别名
- Bcl9L (BCL9L 产品)
- 别名
- BCL9-2 antibody, DLNB11 antibody, B9L antibody, BC003321 antibody, bcl9-2 antibody, BCL9L antibody, B-cell CLL/lymphoma 9 like antibody, B cell CLL/lymphoma 9-like antibody, B-cell CLL/lymphoma 9-like antibody, BCL9L antibody, Bcl9l antibody, bcl9l antibody
- 背景
- Bcl9L Antibody: Bcl9L, a homolog of Bcl9, was initially identified through a bioinformatics screening. It is expressed in fetal brain, adult lung, eye and prostate, in addition to several types of tumors including pancreatic and prostate cancers. Bcl9L has been shown to interact with beta-catenin, a target of the Wnt signaling pathway, and is required for enhanced beta-catenin-T-cell factor (TCF)-mediated transcription in colorectal tumor cells, possibly by translocating beta-catenin to the nucleus. Other studies have indicated that Bcl9L expression correlates with high nuclear grade cancer phenotype and the expression of ErbB2/HER-2 in breast cancers, suggesting that activity may occur in other types of cancer. Bcl9L has also been shown to be critical for Wnt-mediate regulation of stem cell traits in colon epithelium and adenocarcinomas which are associated with tumor invasion, metastasis, and resistance to therapy.
- 分子量
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Predicted: 165 kDa
Observed: 195 kDa - 基因ID
- 283149
- NCBI登录号
- NP_872363
- UniProt
- Q86UU0
- 途径
- Stem Cell Maintenance
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