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BCL9L 抗体 (N-Term)

BCL9L 适用: 人 WB, ELISA, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991496
发货至: 中国
  • 抗原 See all BCL9L 抗体
    BCL9L (B-Cell CLL/lymphoma 9-Like (BCL9L))
    抗原表位
    • 13
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    AA 20-70, N-Term
    适用
    • 27
    • 4
    • 4
    宿主
    • 26
    • 1
    克隆类型
    • 26
    • 1
    多克隆
    标记
    • 10
    • 3
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    • 2
    • 2
    • 1
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    This BCL9L antibody is un-conjugated
    应用范围
    • 19
    • 16
    • 1
    • 1
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    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    Bcl9L antibody is predicted to not cross-react with other Bcl family members. At least four isoforms of Bcl9L are known to exist, this antibody will detect all four.
    纯化方法
    Bcl9L Antibody is affinity chromatography purified via peptide column.
    免疫原
    Bcl9L antibody was raised against a 20 amino acid synthetic peptide near the amino terminus of human Bcl9L. The immunogen is located within amino acids 20 - 70 of Bcl9L.
    亚型
    IgG
    Top Product
    Discover our top product BCL9L Primary Antibody
  • 应用备注
    Bcl9L antibody can be used for detection of Bcl9L by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL and immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Bcl9L Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    Bcl9L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    BCL9L (B-Cell CLL/lymphoma 9-Like (BCL9L))
    别名
    Bcl9L (BCL9L 产品)
    别名
    BCL9-2 antibody, DLNB11 antibody, B9L antibody, BC003321 antibody, bcl9-2 antibody, BCL9L antibody, B-cell CLL/lymphoma 9 like antibody, B cell CLL/lymphoma 9-like antibody, B-cell CLL/lymphoma 9-like antibody, BCL9L antibody, Bcl9l antibody, bcl9l antibody
    背景
    Bcl9L Antibody: Bcl9L, a homolog of Bcl9, was initially identified through a bioinformatics screening. It is expressed in fetal brain, adult lung, eye and prostate, in addition to several types of tumors including pancreatic and prostate cancers. Bcl9L has been shown to interact with beta-catenin, a target of the Wnt signaling pathway, and is required for enhanced beta-catenin-T-cell factor (TCF)-mediated transcription in colorectal tumor cells, possibly by translocating beta-catenin to the nucleus. Other studies have indicated that Bcl9L expression correlates with high nuclear grade cancer phenotype and the expression of ErbB2/HER-2 in breast cancers, suggesting that activity may occur in other types of cancer. Bcl9L has also been shown to be critical for Wnt-mediate regulation of stem cell traits in colon epithelium and adenocarcinomas which are associated with tumor invasion, metastasis, and resistance to therapy.
    分子量
    Predicted: 165 kDa

    Observed: 195 kDa
    基因ID
    283149
    NCBI登录号
    NP_872363
    UniProt
    Q86UU0
    途径
    Stem Cell Maintenance
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