EFHD2 抗体 (N-Term)
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- 抗原 See all EFHD2 抗体
- EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EFHD2 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- EFHD2 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- EFHD2 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human EFHD2. The immunogen is located within the first 50 amino acids of EFHD2.
- 亚型
- IgG
- Top Product
- Discover our top product EFHD2 Primary Antibody
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- 应用备注
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EFHD2 antibody can be used for detection of EFHD2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- EFHD2 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- EFHD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Sertoli cell-enriched proteins in mouse and human testicular interstitial fluid." in: PloS one, Vol. 18, Issue 9, pp. e0290846, (2023) (PubMed).
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Sertoli cell-enriched proteins in mouse and human testicular interstitial fluid." in: PloS one, Vol. 18, Issue 9, pp. e0290846, (2023) (PubMed).
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- 抗原
- EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))
- 别名
- EFHD2 (EFHD2 产品)
- 别名
- SWS1 antibody, efhd2 antibody, EFHD2 antibody, MGC131292 antibody, 2600015J22Rik antibody, AA408606 antibody, D4Wsu27e antibody, si:dkey-72l14.9 antibody, wu:fb80e07 antibody, EF-hand domain family member D2 antibody, EF-hand domain family, member D2 antibody, EF-hand domain family member D2 L homeolog antibody, EF hand domain containing 2 antibody, EFHD2 antibody, Efhd2 antibody, efhd2 antibody, efhd2.L antibody
- 背景
- EFHD2 Antibody: EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLCgamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-κ,B-activating branch.
- 基因ID
- 79180
- NCBI登录号
- NP_077305
- UniProt
- Q96C19
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