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EFHD2 抗体 (N-Term)

EFHD2 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991298
发货至: 中国
  • 抗原 See all EFHD2 抗体
    EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))
    抗原表位
    • 5
    • 3
    • 2
    • 1
    • 1
    N-Term
    适用
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 11
    • 1
    克隆类型
    • 12
    多克隆
    标记
    • 8
    • 2
    • 1
    • 1
    This EFHD2 antibody is un-conjugated
    应用范围
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    纯化方法
    EFHD2 Antibody is affinity chromatography purified via peptide column.
    免疫原
    EFHD2 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human EFHD2. The immunogen is located within the first 50 amino acids of EFHD2.
    亚型
    IgG
    Top Product
    Discover our top product EFHD2 Primary Antibody
  • 应用备注
    EFHD2 antibody can be used for detection of EFHD2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    EFHD2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    EFHD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • ODonnell, Dagley, Curley, Darbey, OShaughnessy, Diemer, Pilatz, Fietz, Stanton, Smith, Rebourcet: "Sertoli cell-enriched proteins in mouse and human testicular interstitial fluid." in: PloS one, Vol. 18, Issue 9, pp. e0290846, (2023) (PubMed).

  • 抗原
    EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))
    别名
    EFHD2 (EFHD2 产品)
    别名
    SWS1 antibody, efhd2 antibody, EFHD2 antibody, MGC131292 antibody, 2600015J22Rik antibody, AA408606 antibody, D4Wsu27e antibody, si:dkey-72l14.9 antibody, wu:fb80e07 antibody, EF-hand domain family member D2 antibody, EF-hand domain family, member D2 antibody, EF-hand domain family member D2 L homeolog antibody, EF hand domain containing 2 antibody, EFHD2 antibody, Efhd2 antibody, efhd2 antibody, efhd2.L antibody
    背景
    EFHD2 Antibody: EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLCgamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-κ,B-activating branch.
    基因ID
    79180
    NCBI登录号
    NP_077305
    UniProt
    Q96C19
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