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TMEM38B 抗体 (C-Term)

TMEM38B 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991240
发货至: 中国
  • 抗原 See all TMEM38B 抗体
    TMEM38B (Transmembrane Protein 38B (TMEM38B))
    抗原表位
    • 6
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 9
    • 3
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 9
    克隆类型
    • 9
    多克隆
    标记
    • 5
    • 2
    • 1
    • 1
    This TMEM38B antibody is un-conjugated
    应用范围
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    TMEM38B Antibody is affinity chromatography purified via peptide column.
    免疫原
    TMEM38B antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human TMEM38B. The immunogen is located within the last 50 amino acids of TMEM38B.
    亚型
    IgG
    Top Product
    Discover our top product TMEM38B Primary Antibody
  • 应用备注
    TMEM38B antibody can be used for detection of TMEM38B by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    TMEM38B Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    TMEM38B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    TMEM38B (Transmembrane Protein 38B (TMEM38B))
    别名
    TMEM38B (TMEM38B 产品)
    别名
    zgc:55815 antibody, tricb antibody, tric-b antibody, MGC83592 antibody, DKFZp469C0220 antibody, C9orf87 antibody, D4Ertd89e antibody, OI14 antibody, TRIC-B antibody, TRICB antibody, bA219P18.1 antibody, 1600017F22Rik antibody, AA437809 antibody, AV051057 antibody, mg33b antibody, RGD1305703 antibody, transmembrane protein 38B antibody, transmembrane protein 38B L homeolog antibody, tmem38b antibody, TMEM38B antibody, tmem38b.L antibody, Tmem38b antibody
    背景
    TMEM38B Antibody: TMEM38A and TMEM38B are two recently identified trimeric intracellular cation (TRIC) channel subtypes. TMEM38B is expressed in most mammalian tissues, while TMEM38A is preferentially expressed in excitable tissues such as striated muscle and brain. Mice deficient in both TMEM38A and TMEM38B suffer embryonic cardiac failure, the cardiac myocytes display severe dysfunction in SR Ca2+ handling, weakened Ca2+ release, and reduced K+ permeability indicating that the TRIC cation channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores. Mice that were lacking only TMEM38B however, die shortly after birth due to respiratory failure and have lungs exhibiting severe histological defect and ultrastructural abnormalities in their alveolar type II epithelial cells, indicating that TMEM38B are essential for perinatal lung maturation. Other experiments have shown that TMEM38A and TMEM38B can act with junctophilin proteins to support efficient ryanodine receptor-mediated Ca2+ release in muscle cells.
    基因ID
    55151
    NCBI登录号
    NP_060582
    UniProt
    Q9NVV0
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