FRMPD4 抗体 (AA 620-670)
FRMPD4
适用: 人
WB, ELISA, IHC (p), IF
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all FRMPD4 抗体
- FRMPD4 (FERM and PDZ Domain Containing 4 (FRMPD4))
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抗原表位
- AA 620-670
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FRMPD4 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- FRMPD4 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- FRMPD4 antibody was raised against an 18 amino acid synthetic peptide from near the center of human FRMPD4. The immunogen is located within amino acids 620 - 670 of FRMPD4.
- 亚型
- IgG
- Top Product
- Discover our top product FRMPD4 Primary Antibody
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anti-FERM and PDZ Domain Containing 4 (FRMPD4) (Center) antibody
FRMPD4 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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FRMPD4 antibody can be used for detection of FRMPD4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- FRMPD4 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- FRMPD4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- FRMPD4 (FERM and PDZ Domain Containing 4 (FRMPD4))
- 别名
- FRMPD4 (FRMPD4 产品)
- 别名
- RGD1566031 antibody, PDZD10 antibody, PDZK10 antibody, Gm196 antibody, PKAP1 antibody, Pdzd10 antibody, Pdzk10 antibody, Preso1 antibody, FERM and PDZ domain containing 4 antibody, Frmpd4 antibody, FRMPD4 antibody, frmpd4 antibody
- 背景
- FRMPD4 Antibody: The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. FRMPD4, also known as Preso, also contains another protein interaction domain termed WW (domain with two conserved Trp residues) at its amino terminus. It was identified through a yeast two-hybrid screen using the PDZ domain of PSD-95 as bait and is highly expressed in multiple regions of the brain and is enriched in the postsynaptic density (PSD) fractions. Overexpression of FRMPD4 in cultured hippocampal neurons significantly increased the linear density of dendritic spines without changing their length and width, conversely, knockdown experiments using RNAi caused a decrease in spine density, indicating FRMPD4 positively regulates dendritic spine density but not morphology. The decreased level of FRMPD4 also resulted in reduced levels of excitatory synaptic transmission, suggesting that FRMPD4 is required for maintenance of excitatory synaptic transmission.
- 基因ID
- 9772
- UniProt
- Q12767
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