RWDD3 抗体 (N-Term)
RWDD3
适用: 人, 小鼠, 大鼠
WB, ELISA
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all RWDD3 抗体
- RWDD3 (RWD Domain Containing 3 (RWDD3))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RWDD3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- RWDD3 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- RWDD3 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human RWDD3. The immunogen is located within the first 50 amino acids of RWDD3.
- 亚型
- IgG
- Top Product
- Discover our top product RWDD3 Primary Antibody
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anti-RWD Domain Containing 3 (RWDD3) (C-Term) antibody
RWDD3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RWD Domain Containing 3 (RWDD3) (N-Term) antibodyRWDD3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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RWDD3 antibody can be used for detection of RWDD3 by Western blot at 0.5 μ,g/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- RWDD3 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- RWDD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- RWDD3 (RWD Domain Containing 3 (RWDD3))
- 别名
- RWDD3 (RWDD3 产品)
- 别名
- DKFZp469N1913 antibody, RSUME antibody, 2510027J23Rik antibody, 3110037C01Rik antibody, AI035684 antibody, AI662458 antibody, X2CR1 antibody, X2cr1 antibody, zgc:73229 antibody, RWD domain containing 3 antibody, RWDD3 antibody, rwdd3 antibody, Rwdd3 antibody
- 背景
- RWDD3 Antibody: RWDD3 (RSUME), a small RWD-containing protein, has a central role in sumoylation by enhancing SUMO conjugation in the regulatory network of immune-inflammatory signals. RWDD3 increases Iκ,Beta sumoylation and stability. In addition, RWDD3 inhibits TNF-α,-induced kappaB-LUC (Luciferase) reporter activity, showing the functional consequence of Iκ,Beta increased stability. RSUME-enhanced sumoylation of Iκ,Beta leads to the inhibition of NF-κ,Beta activity on two well-known inflammatory genes, IL-8 and cyclooxygenase-2 (Cox-2) and therefore may also favor anti-inflammatory pathways. Expression of RWDD3 was induced under hypoxic conditions and it has a potential role during vascularization. Both BMP-4 and RWDD3 may be interesting targets for inhibiting steps involved in pituitary tumorigenesis.
- 基因ID
- 25950
- NCBI登录号
- NP_056300
- UniProt
- Q9Y3V2
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