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SYPL2 抗体 (C-Term)

SYPL2 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991151
发货至: 中国
  • 抗原 See all SYPL2 抗体
    SYPL2 (Synaptophysin-Like 2 (SYPL2))
    抗原表位
    C-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 1
    克隆类型
    • 1
    多克隆
    标记
    • 1
    This SYPL2 antibody is un-conjugated
    应用范围
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    At least two isoforms of SYPL2 are known to exist. SYPL2 antibody will not cross-react with SYPL1.
    纯化方法
    SYPL2 Antibody is affinity chromatography purified via peptide column.
    免疫原
    SYPL2 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human SYPL. The immunogen is located within the last 50 amino acids of SYPL2.
    亚型
    IgG
    Top Product
    Discover our top product SYPL2 Primary Antibody
  • 应用备注
    SYPL2 antibody can be used for detection of SYPL2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    SYPL2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    SYPL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    SYPL2 (Synaptophysin-Like 2 (SYPL2))
    别名
    SYPL2 (SYPL2 产品)
    别名
    AI552439 antibody, Mg29 antibody, MG29 antibody, mg29 antibody, MGC88982 antibody, Sypl antibody, fc22a07 antibody, wu:fc22a07 antibody, zgc:110355 antibody, sypl antibody, wu:fd54d09 antibody, zgc:65838 antibody, synaptophysin-like 2 antibody, synaptophysin like 2 antibody, synaptophysin like 2 S homeolog antibody, synaptophysin-like 2b antibody, synaptophysin-like 2a antibody, Sypl2 antibody, SYPL2 antibody, sypl2.S antibody, sypl2 antibody, sypl2b antibody, sypl2a antibody
    背景
    SYPL2 Antibody: SYPL2, also known as Mitsugumin 29, was initially identified as a transmembrane protein from the triad junction in skeletal muscle that had significant homology with members of the synaptophysin family. SYPL2 is thought to participate in the excitation-contraction coupling process of skeletal muscle as SYPL2-null mice showed reduced muscle contractile force and altered triad junction structure and increased susceptibility to fatigue of the skeletal muscle. SYPL2 plays a critical role in muscle Ca2+ signaling by regulating the process of store-operated Ca2+ entry and interacts with ryanodine receptor (RyR), thereby influencing intracellular Ca2+ homeostasis through changes in the RyR/Ca2+ release function. Co-expression of SYPL2 and RyR in cultured cells leads to apoptotic cell death resulting from the depletion of Ca2+ from the intracellular stores.
    基因ID
    284612
    NCBI登录号
    NP_001035799
    UniProt
    Q5VXT5
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