GPR3 抗体 (C-Term)
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- 抗原 See all GPR3 抗体
- GPR3 (G Protein-Coupled Receptor 3 (GPR3))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GPR3 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- GPR3 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- GPR3 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human GPR3. The immunogen is located within the last 50 amino acids of GPR3.
- 亚型
- IgG
- Top Product
- Discover our top product GPR3 Primary Antibody
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anti-G Protein-Coupled Receptor 3 (GPR3) (AA 1-330) antibody
GPR3 适用: 人 ELISA, WB, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3B4-G3 unconjugated
anti-G Protein-Coupled Receptor 3 (GPR3) (AA 300-330) antibodyGPR3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 3 (GPR3) (Extracellular Domain) antibodyGPR3 适用: 人, 小鼠, 大鼠, 猴, Hamster IHC, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 3 (GPR3) (AA 1-331) antibodyGPR3 适用: 人 ELISA, WB, IHC, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3B4-G3 unconjugated
anti-G Protein-Coupled Receptor 3 (GPR3) (Extracellular Domain) antibodyGPR3 适用: 人, 猴, Cow, 兔 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 3 (GPR3) (Extracellular Domain) antibodyGPR3 适用: 人, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 3 (GPR3) (AA 1-330) antibodyGPR3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 3 (GPR3) (Internal Region) antibodyVerified GPR3 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 3 (GPR3) (C-Term) antibodyGPR3 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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GPR3 antibody can be used for detection of GPR3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- GPR3 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- GPR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- GPR3 (G Protein-Coupled Receptor 3 (GPR3))
- 别名
- GPR3 (GPR3 产品)
- 别名
- GPR3 antibody, ACCA antibody, Gpcr3 antibody, Gpcr20 antibody, Gpcr21 antibody, G protein-coupled receptor 3 antibody, G-protein coupled receptor 3 antibody, GPR3 antibody, Gpr3 antibody
- 背景
- GPR3 Antibody: GPR3, also known as ACCA, is a G-protein coupled receptor that constitutively activates adenylate cyclase and is highly expressed in the central nervous system. Overexpression of GPR3 stimulates the production of amyloid-beta peptide (Abeta), the deposition of which is one of the pathological hallmarks of Alzheimer 's disease (AD), while the ablation of GPR3 prevented the accumulation of Abeta in vitro and in an AD mouse model. This is of particular interest because of the proximity of a reported candidate Alzheimer 's disease (AD) locus, suggesting that GPR3 may be a potential therapeutic target for the treatment of AD. GPR3 has also been shown to block the proliferation of cerebellar granule cell precursors (GCP) during postnatal development by inhibiting the Shh-induced proliferation of GCP, indicating that GPR3 activation may represent one of the signals that triggers the postnatal cell cycle exit and terminal differentiation of GPCs.
- 分子量
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Predicted: 36 kDa
Observed: 36 kDa - 基因ID
- 2827
- UniProt
- P46089
- 途径
- cAMP Metabolic Process
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