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Nanos Homolog 1 抗体 (N-Term)

NANOS1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990936
发货至: 中国
  • 抗原 See all Nanos Homolog 1 (NANOS1) 抗体
    Nanos Homolog 1 (NANOS1)
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 43
    • 12
    • 6
    • 3
    • 3
    • 1
    宿主
    • 41
    • 1
    • 1
    克隆类型
    • 42
    • 1
    多克隆
    标记
    • 22
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Nanos Homolog 1 antibody is un-conjugated
    应用范围
    • 30
    • 21
    • 17
    • 6
    • 6
    • 3
    • 3
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Nanos1 Antibody is affinity chromatography purified via peptide column.
    免疫原
    Nanos1 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human Nanos1. The immunogen is located within the first 50 amino acids of Nanos1.
    亚型
    IgG
    Top Product
    Discover our top product NANOS1 Primary Antibody
  • 应用备注
    Nanos1 antibody can be used for detection of Nanos1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Nanos1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    Nanos1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    Nanos Homolog 1 (NANOS1)
    别名
    Nanos1 (NANOS1 产品)
    别名
    NOS1 antibody, nanos1 antibody, fb76c12 antibody, wu:fb93h11 antibody, wu:fb98e07 antibody, wu:fq21a10 antibody, Xcat-2 antibody, nos1 antibody, xnos1 antibody, xcat-2 antibody, LOC100144352 antibody, NANOS1A antibody, nanos C2HC-type zinc finger 1 antibody, nanos homolog 1 antibody, nanos homolog 1 (Drosophila) antibody, nanos homolog 1 L homeolog antibody, Nanos homolog 1 antibody, nanos1 antibody, NANOS1 antibody, nanos1 antibody, Nanos1 antibody, nanos1.L antibody, nano1 antibody, nanos1a antibody
    背景
    Nanos1 Antibody: Nanos1 is one of three known mammalian homologs to the Drosophila gene nanos. Nanos1 is an RNA-binding protein containing a zinc-finger motif and is expressed in the developing nervous system and continues in the adult brain. Interestingly, unlike mice deficient in either nanos2 or nanos3, mice lacking the nanos1 gene develop normally with no sign of abnormalities. Recently it has been found that expression of nanos1 mRNA is down-regulated by E-cadherin in a human breast cancer cell line and the amino-terminal domain on Nanos1 interacts with the E-cadherin-binding protein p120ctn. Furthermore, overexpression of Nanos1 in human colorectal DLD1 cancer cells functionally abolished cell-cell adhesion, allowing the cancer cells to develop strong migratory and invasive properties. These results suggest that targeting Nanos1 might prove an effective strategy in the treatment of E-cadherin-negative tumors.
    基因ID
    340719
    UniProt
    Q8WY41
    途径
    Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction
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