BICD2 抗体 (AA 300-350)
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- 抗原 See all BICD2 抗体
- BICD2 (Bicaudal D Homolog 2 (BICD2))
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抗原表位
- AA 300-350
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BICD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- This BICD2 antibody will not cross-react with BICD1.
- 纯化方法
- BICD2 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- BICD2 antibody was raised against a 14 amino acid synthetic peptide from near the center of human BICD2. The immunogen is located within amino acids 300 - 350 of BICD2.
- 亚型
- IgG
- Top Product
- Discover our top product BICD2 Primary Antibody
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anti-Bicaudal D Homolog 2 (BICD2) (AA 511-625) antibody
BICD2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bicaudal D Homolog 2 (BICD2) (AA 440-620) antibodyBICD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bicaudal D Homolog 2 (BICD2) (AA 787-818), (C-Term) antibodyBICD2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15418 unconjugated
anti-Bicaudal D Homolog 2 (BICD2) (C-Term) antibodyBICD2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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BICD2 antibody can be used for detection of BICD2 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- BICD2 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- BICD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- BICD2 (Bicaudal D Homolog 2 (BICD2))
- 别名
- BICD2 (BICD2 产品)
- 别名
- SMALED2 antibody, bA526D8.1 antibody, 0610027D24Rik antibody, 1110005D12Rik antibody, AA408834 antibody, mKIAA0699 antibody, MGC84972 antibody, BICD2 antibody, bicd2 antibody, BICD cargo adaptor 2 antibody, bicaudal D homolog 2 (Drosophila) antibody, BICD cargo adaptor 2 L homeolog antibody, zgc:171572 antibody, BICD2 antibody, Bicd2 antibody, bicd2.L antibody, bicd2 antibody, zgc:171572 antibody
- 背景
- BICD2 Antibody: BICD2 is the second human homolog discovered to the Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. Similar to the highly homologous protein BICD1, BICD2 can bind to dynein-dynactin complex, primarily through the dynamitin subunit of dynactin. The C-terminus of BICD2 targets the protein to the Golgi complex while the N-terminal domain of BICD2 co-immunoprecipitates with cytoplasmic dynein, suggesting BICD2 plays a role in the dynein-dynactin interaction on the surface of membranous organelles. Mice engineered to overexpress the BICD2 amino terminal domain in neurons developed amyotrophic lateral sclerosis (ALS)-like features such as Golgi fragmentation, neurofilament swelling in proximal axons, etc., suggesting that impaired dynein/dynactin function may explain some of the pathological features observed in ALS patients.
- 分子量
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Predicted: 94 kDa
Observed: 100 kDa - 基因ID
- 23299
- UniProt
- Q8TD16
- 途径
- Maintenance of Protein Location
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