FBXL20 抗体 (N-Term)
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- 抗原 See all FBXL20 抗体
- FBXL20 (F-Box and Leucine-Rich Repeat Protein 20 (FBXL20))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FBXL20 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- SCRAPPER Antibody is affinity chromatography purified via peptide column.
- 免疫原
- SCRAPPER antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of the human SCRAPPER. The immunogen is located within the first 50 amino acids of SCRAPPER.
- 亚型
- IgG
- Top Product
- Discover our top product FBXL20 Primary Antibody
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anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (AA 1-436) antibody
FBXL20 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (AA 176-225) antibodyFBXL20 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (AA 110-159) antibodyFBXL20 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (N-Term) antibodyFBXL20 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (C-Term) antibodyFBXL20 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (Middle Region) antibodyFBXL20 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (N-Term) antibodyFBXL20 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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SCRAPPER antibody can be used for detection of SCRAPPER by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- SCRAPPER Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- SCRAPPER antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- FBXL20 (F-Box and Leucine-Rich Repeat Protein 20 (FBXL20))
- 别名
- SCRAPPER (FBXL20 产品)
- 别名
- Fbl2 antibody, Fbl20 antibody, fbl20 antibody, MGC81000 antibody, scrapper antibody, FBL2 antibody, 2610511F20Rik antibody, 4632423N09Rik antibody, AI849362 antibody, AL117906 antibody, C86145 antibody, Scr antibody, mKIAA4147 antibody, FBXL2 antibody, Fbxl2 antibody, F-box and leucine rich repeat protein 20 antibody, F-box and leucine-rich repeat protein 20 L homeolog antibody, F-box and leucine-rich repeat protein 20 antibody, F-box/LRR-repeat protein 20 antibody, putative fbxl20 antibody, F-box and leucine rich repeat protein 2 antibody, FBXL20 antibody, fbxl20.L antibody, LOAG_14232 antibody, LOC100080065 antibody, Smp_097020.1 antibody, FBXL2 antibody, Fbxl20 antibody
- 背景
- SCRAPPER Antibody: Members of the F-box protein family, such as Scrapper, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. Scrapper is selectively expressed in the brain, broadly expressed within the mouse CNS and is abundant at presynaptic membrane. Scrapper has orthologs in C. elegans, D. melanogaster, and mammals which suggests that it might function as an important membrane-localized E3 ligase in various species. Scrapper is a major presynaptic E3 ubiquitin ligase that acts through RIM1a via degradation and the ubiquitin-proteasome-system (UPS) pathway to critically regulate synaptic transmission. This identifies protein degradation as a mechanism for holding synaptic communication in check.
- 基因ID
- 84961
- NCBI登录号
- NP_116264
- UniProt
- Q96IG2
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