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DLGAP3 抗体 (C-Term)

DLGAP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990832
发货至: 中国
  • 抗原 See all DLGAP3 抗体
    DLGAP3 (Discs, Large (Drosophila) Homolog-Associated Protein 3 (DLGAP3))
    抗原表位
    • 8
    • 8
    • 6
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 17
    克隆类型
    • 17
    多克隆
    标记
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    This DLGAP3 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    纯化方法
    SAPAP3 Antibody is affinity chromatography purified via peptide column.
    免疫原
    SAPAP3 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human SAPAP3. The immunogen is located within the last 50 amino acids of SAPAP3.
    亚型
    IgG
    Top Product
    Discover our top product DLGAP3 Primary Antibody
  • 应用备注
    SAPAP3 antibody can be used for detection of SAPAP3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    SAPAP3 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    SAPAP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    DLGAP3 (Discs, Large (Drosophila) Homolog-Associated Protein 3 (DLGAP3))
    别名
    SAPAP3 (DLGAP3 产品)
    别名
    DAP3 antibody, SAPAP3 antibody, BC058433 antibody, DAP-3 antibody, Prpl8 antibody, Sapap3 antibody, Dap3 antibody, DLG associated protein 3 antibody, discs, large (Drosophila) homolog-associated protein 3 antibody, DLGAP3 antibody, Dlgap3 antibody, dlgap3 antibody
    背景
    SAPAP3 Antibody: SAP90/PSD-95-associated protein 3 (SAPAP3, also known as DLGAP3) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP3 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). Both SAPAP3 protein and mRNA are targeted to dendrites, whereas SAPAP1, -2, and -4 mRNAs are detected mainly in cell bodies. Recent experiments have suggested that SAPAP3 may be involved in obsessive-compulsive disorder (OCD), as mice lacking SAPAP3 exhibited OCD-like symptoms which could be relieved by lentiviral-mediated selective expression of SAPAP3 in the striatum of SAPAP3-mutant mice. At least two isoforms are known to exist.
    基因ID
    58512
    UniProt
    O95886
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