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SP110 抗体 (C-Term)

SP110 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990830
发货至: 中国
  • 抗原 See all SP110 抗体
    SP110 (SP110 Nuclear Body Protein (SP110))
    抗原表位
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 470-520, C-Term
    适用
    • 21
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 15
    • 6
    克隆类型
    • 18
    • 3
    多克隆
    标记
    • 18
    • 1
    • 1
    • 1
    This SP110 antibody is un-conjugated
    应用范围
    • 18
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    纯化方法
    IPR1 Antibody is affinity chromatography purified via peptide column.
    免疫原
    IPR1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human IPR1. The immunogen is located within amino acids 470 - 520 of IPR1.
    亚型
    IgG
    Top Product
    Discover our top product SP110 Primary Antibody
  • 应用备注
    Ipr1 antibody can be used for detection of Ipr1 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    IPR1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    IPR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    SP110 (SP110 Nuclear Body Protein (SP110))
    别名
    IPR1 (SP110 产品)
    别名
    SP110 antibody, IFI41 antibody, IFI75 antibody, IPR1 antibody, VODI antibody, 5031415C07Rik antibody, 52kDa antibody, 5830484A20Rik antibody, ENSMUSG00000075603 antibody, Ifi75 antibody, Ipr1 antibody, SP110 nuclear body protein antibody, Sp110 nuclear body protein antibody, SP110 antibody, Sp110 antibody
    背景
    IPR1 Antibody: Susceptibility to tuberculosis (TB) in mice has recently been attributed to the IPR1 gene. IPR1 is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. SP110 is the closest homolog of the IPR1 protein in humans. The IPR1/Sp110 gene product might play a role in integrating signals generated by intracellular pathogens with mechanisms controlling innate immunity, cell death, and pathogenesis. IPR1/Sp110 is up-regulated after infection with M. tuberculosis and required by Anaplasma phagocytophilum for infection of human promyelocytic cells. Defects in Sp110 are a cause of severely impaired resistance to infection by M. tuberculosis.
    基因ID
    3431
    NCBI登录号
    NP_004501
    UniProt
    Q9HB58
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