GRIK4 抗体 (C-Term)
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- 抗原 See all GRIK4 抗体
- GRIK4 (Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GRIK4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- Grik4 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Grik4 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of the mouse Grik4. The immunogen is located within the last 50 amino acids of Grik4.
- 亚型
- IgG
- Top Product
- Discover our top product GRIK4 Primary Antibody
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anti-Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4) (AA 21-166) antibody
GRIK4 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 8H5G5 unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4) (AA 826-956) antibodyGRIK4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4) (AA 21-130) antibodyGRIK4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4) (AA 225-447) antibodyGRIK4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4) (AA 21-220) antibodyGRIK4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4) (AA 49-61), (Extracellular), (N-Term) antibodyGRIK4 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4) (N-Term) antibodyGRIK4 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4) (C-Term) antibodyGRIK4 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Grik4 antibody can be used for detection of Grik4 by Western blot at 0.5 - 2 μ,g/mL. Despite its predicted molecular weight, Grik4 often migrates at a lower molecular weight in SDS-PAGE. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Grik4 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- Grik4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- GRIK4 (Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4))
- 别名
- Grik4 (GRIK4 产品)
- 别名
- GRIK4 antibody, ka1 antibody, eaa1 antibody, EAA1 antibody, GRIK antibody, GluK4 antibody, KA1 antibody, 6330551K01Rik antibody, GluRgamma1 antibody, KA-1 antibody, glutamate receptor, ionotropic, kainate 4 antibody, glutamate ionotropic receptor kainate type subunit 4 antibody, glutamate receptor, ionotropic, kainate 4 L homeolog antibody, grik4 antibody, GRIK4 antibody, grik4.L antibody, Grik4 antibody
- 背景
- Grik4 Antibody: Grik4 codes for the KA1 subunit of kainate-type ionotropic glutamate receptors which are critical regulators of network activity that act by modifying neuronal excitability, directly and indirectly, through GABAergic interneurons. Five subunits can assemble to form kainate receptors (KARs): GluR5 (coded by Grik1), GluR6 (coded by Grik2), and GluR7 (coded by Grik3) are the low-affinity subunits, and KA1 and KA2 are the high-affinity subunits. In the adult brain, KARs are located pre- and postsynaptically on pyramidal cells and on interneurons. Kainate receptors on GABA-containing interneurons enhance GABA release and thereby downregulate glutamatergic signaling. KARs have been implicated in numerous psychiatric disorders. Case control studies show significant association of Grik4 with both schizophrenia and bipolar disorder.
- 基因ID
- 110637
- NCBI登录号
- NP_780690
- UniProt
- Q8BMF5
- 途径
- Synaptic Membrane
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