NPAS3 抗体 (AA 470-520)
NPAS3
适用: 人, 小鼠, 大鼠
WB, ELISA, IHC (p), IF
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all NPAS3 抗体
- NPAS3 (Neuronal PAS Domain Protein 3 (NPAS3))
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抗原表位
- AA 470-520
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NPAS3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- NPAS3 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- NPAS3 antibody was raised against a 28 amino acid synthetic peptide from near the center of human NPAS3. The immunogen is located within amino acids 470 - 520 of NPAS3.
- 亚型
- IgG
- Top Product
- Discover our top product NPAS3 Primary Antibody
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anti-Neuronal PAS Domain Protein 3 (NPAS3) (N-Term) antibody
NPAS3 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Neuronal PAS Domain Protein 3 (NPAS3) (Middle Region) antibodyNPAS3 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 山羊, 斑马鱼, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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NPAS3 antibody can be used for detection of NPAS3 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- NPAS3 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- NPAS3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- NPAS3 (Neuronal PAS Domain Protein 3 (NPAS3))
- 别名
- NPAS3 (NPAS3 产品)
- 别名
- trh antibody, mop6 antibody, pasd6 antibody, MGC145768 antibody, MOP6 antibody, PASD6 antibody, bHLHe12 antibody, 4930423H22Rik antibody, neuronal PAS domain protein 3 antibody, npas3 antibody, NPAS3 antibody, Npas3 antibody
- 背景
- NPAS3 Antibody: Neuronal PAS domain protein 3 (NPAS3) is a brain-enriched basic helix-loop-helix PAS domain transcription factor and is broadly expressed in the developing neuroepithelium and has recently found to be disrupted by genetic translocation in a family affected with schizophrenia. It was recently shown to be involved in the regulation of FGF signaling in the dentate gyrus by controlling the expression of the FGF receptor subtype 1 and in turn neurogenesis emanating from this region. NPAS3-null mice were growth-retarded and displayed brain defects that included reduced size of the anterior hippocampus, hypoplasia of the corpus callosum, and enlargement of the ventricles, as well as several behavioral abnormalities. Furthermore, these NPAS3-null mice also exhibited disruptions in several neurosignaling pathways involving glutamate, dopamine, and serotonin. These results demonstrate the essential role played by NPAS3 during structural and functional brain development. At least three isoforms of NPAS3 are known to exist.
- 基因ID
- 64067
- UniProt
- Q8IXF0
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