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SCO2 抗体 (C-Term)

SCO2 适用: 人 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990718
发货至: 中国
  • 抗原 See all SCO2 抗体
    SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))
    抗原表位
    • 8
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    C-Term
    适用
    • 21
    • 2
    • 1
    宿主
    • 19
    • 2
    克隆类型
    • 21
    多克隆
    标记
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    This SCO2 antibody is un-conjugated
    应用范围
    • 20
    • 13
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    纯化方法
    SCO2 Antibody is affinity chromatography purified via peptide column.
    免疫原
    SCO2 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human SCO2. The immunogen is located within the last 50 amino acids of SCO2.
    亚型
    IgG
    Top Product
    Discover our top product SCO2 Primary Antibody
  • 应用备注
    SCO2 antibody can be used for detection of SCO2 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    SCO2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    SCO2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))
    别名
    SCO2 (SCO2 产品)
    别名
    CEMCOX1 antibody, MYP6 antibody, SCO1L antibody, SCO cytochrome oxidase deficient homolog 2 (yeast) antibody, SCO2 cytochrome c oxidase assembly protein antibody, SCO2, cytochrome c oxidase assembly protein antibody, SCO2 antibody, Sco2 antibody
    背景
    SCO2 Antibody: Synthesis of cytochrome c oxidase 2 was initially identified in yeast as one of two cytochrome c oxidase (COX) assembly proteins that enable the assembly of cytochrome c holoenzyme, a complex that catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Like their yeast homologs, the function of both SCO2 and SCO1 are dependent on copper ion binding. Recent studies suggest that SCO2 expression is regulated by p53, so that a decrease in p53 expression, such as in numerous tumors and cells lines, the drop in SCO2 expression leads to a shift from normal aerobic respiration towards the production of glycolytic ATP. Defects in the SCO2 protein are also associated with fatal infantile cardioencephalomyopathy and COX deficiency.
    分子量
    Predicted: 29 kDa

    Observed: 33 kDa
    基因ID
    9997
    UniProt
    O43819
    途径
    Transition Metal Ion Homeostasis, Warburg Effect
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