Cyclin O 抗体 (AA 90-140)
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- 抗原 See all Cyclin O (CCNO) 抗体
- Cyclin O (CCNO)
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抗原表位
- AA 90-140
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cyclin O antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 特异性
- At least two isoforms of Cyclin O are known to exist, this antibody will recognize both isoforms.
- 纯化方法
- Cyclin O Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Cyclin O antibody was raised against a 13 amino acid synthetic peptide from near the center of human Cyclin O. The immunogen is located within amino acids 90 - 140 of Cyclin O.
- 亚型
- IgG
- Top Product
- Discover our top product CCNO Primary Antibody
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anti-Cyclin O (CCNO) (AA 1-257) antibody
CCNO 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin O (CCNO) (AA 1-350) antibodyCCNO 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin O (CCNO) antibodyCCNO 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Cyclin O antibody can be used for the detection of Cyclin O by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Cyclin O Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- Cyclin O antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- Cyclin O (CCNO)
- 别名
- Cyclin O (CCNO 产品)
- 别名
- RGD1565217 antibody, ccnu antibody, udg2 antibody, ung2 antibody, CCNU antibody, MGC131111 antibody, C86987 antibody, Ccnu antibody, E130318K11 antibody, Ung2 antibody, UDG2 antibody, cyclin O antibody, cyclin O L homeolog antibody, Ccno antibody, ccno antibody, CCNO antibody, ccno.L antibody
- 背景
- Cyclin O Antibody: Cyclin O, also known as CCNO, has recently been identified as a Cdk1- and Cdk2-activating cyclin specific to apoptosis in lymphoid cells. Cyclin O binds to and activates Cdk2 in response to instrinsic apoptotic stimuli such as glucocorticoids or DNA-damaging agents. Supression of Cyclin O expression by shRNA leads to the inhibition of glucocorticoid and DNA-damage-induced apoptosis due to a failure of apical caspase activation while leaving the CD95 death receptor-mediated apoptosis intact. Note: this gene, which had a previous symbol of UNG2, was erroneously identified as a uracil DNA glycosylase. A later publication identified this gene's product as a cyclin protein family member.
- 分子量
- 39 kDa
- 基因ID
- 10309
- NCBI登录号
- NP_066970
- UniProt
- P22674
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