DRAM 抗体 (C-Term)
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- 抗原 See all DRAM (DRAM1) 抗体
- DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))
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抗原表位
- AA 170-220, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DRAM antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- DRAM Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Anti-DRAM antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human DRAM. The immunogen is located within amino acids 170-220 of DRAM.
- 亚型
- IgG
- Top Product
- Discover our top product DRAM1 Primary Antibody
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anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (AA 50-100) antibody
DRAM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (AA 70-119) antibodyDRAM1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (AA 100-200) antibodyDRAM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (N-Term) antibodyDRAM1 适用: 人, 小鼠, 大鼠, 马, 兔, Cow, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (C-Term) antibodyDRAM1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (N-Term) antibodyDRAM1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: 1 μ,g/mL, IF: 20 μ,g/mL, IHC: 2.5 μ,g/mL.
Antibody validated: Western Blot in human, mouse and rat samples, Immunofluorescence and Immunohistochemistry in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- DRAM Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- DRAM antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))
- 别名
- DRAM (DRAM1 产品)
- 别名
- DRAM1 antibody, DRAM antibody, 1200002N14Rik antibody, Dram antibody, dram antibody, DNA damage regulated autophagy modulator 1 antibody, DNA-damage regulated autophagy modulator 1 antibody, DNA damage regulated autophagy modulator 1 L homeolog antibody, DRAM1 antibody, Dram1 antibody, dram1.L antibody
- 背景
- DRAM Antibody: Damage-regulated autophagy modulator (DRAM) is a p53 target gene encoding a lysosomal protein that induces autophagy, a process that degrades cytosolic proteins and organelles. It has been suggested that activation of DRAM by p53 is simultaneous to the activation by p53 of one or more proapoptotic genes such as PUMA, Bax, etc., and that the signaling pathways regulated by these genes promote a full cell death response. By itself, DRAM cannot induce apoptosis, but the fact that it is inactivated in certain cancers highlights the importance of DRAM and suggests that autophagy may play a more important role in cancer than initially suspected. At least two different isoforms of DRAM are known to exist.
- 分子量
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Predicted: 14kD, 26kD
Observed: 14 kD, 26kD kDa - 基因ID
- 55332
- UniProt
- Q8N682
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