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LAMP2 抗体 (C-Term)

LAMP2 适用: 人, 小鼠 WB, ELISA, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990579
发货至: 中国
  • 抗原 See all LAMP2 抗体
    LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
    抗原表位
    • 16
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    C-Term
    适用
    • 115
    • 72
    • 34
    • 16
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    人, 小鼠
    宿主
    • 87
    • 42
    • 30
    克隆类型
    • 80
    • 78
    多克隆
    标记
    • 53
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    This LAMP2 antibody is un-conjugated
    应用范围
    • 110
    • 54
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    • 13
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    • 10
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    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    LAMP-2 antibody cross reacts with LAMP2B and LAMP2C, but not LAMP2A.
    纯化方法
    LAMP-2 Antibody is affinity chromatography purified via peptide column.
    免疫原
    LAMP-2 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human LAMP-2. The immunogen is located within the last 50 amino acids of LAMP-2.
    亚型
    IgG
    Top Product
    Discover our top product LAMP2 Primary Antibody
  • 应用备注
    LAMP-2 antibody can be used for the detection of LAMP-2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL and immunohistochemistry starting at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunocytochemistry in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    LAMP-2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    LAMP-2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
    别名
    LAMP-2 (LAMP2 产品)
    别名
    CD107b antibody, LAMP-2 antibody, LAMPB antibody, LGP110 antibody, Lamp-2 antibody, Lamp-2a antibody, Lamp-2b antibody, Lamp-2c antibody, Mac3 antibody, cd107b antibody, lamp-2 antibody, lampb antibody, LAMP2 antibody, lamp2 antibody, DKFZp459J126 antibody, LGP-B antibody, sb:cb587 antibody, wu:fb14a06 antibody, zgc:103532 antibody, lysosomal associated membrane protein 2 antibody, lysosomal-associated membrane protein 2 antibody, lysosomal-associated membrane protein 2 S homeolog antibody, lysosomal membrane glycoprotein 2 antibody, LAMP2 antibody, Lamp2 antibody, lamp2.S antibody, lamp2 antibody
    背景
    LAMP-2 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components and is negatively regulated by TOR (Target of rapamycin). LAMP-2, a highly glycosylated protein associated with the lysosome, has recently been shown to be important in autophagy as mice deficient in this protein failed to convert autophagic vacuoles into vacuoles leading to impaired degradation of long-lived proteins. This correlates with the finding that human LAMP-2 deficiency causing Danon's disease is associated with the accumulation of autophagic material in striated myocytes. LAMP-2 exists in multiple isoforms.
    基因ID
    16784
    NCBI登录号
    NP_054701
    UniProt
    P17047
    途径
    Autophagy
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