Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
特异性
These proteins often migrate in SDS-PAGE at positions other than their predicted size.
纯化方法
CTRP6 Antibody is affinity chromatography purified via peptide column.
免疫原
CTRP6 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human CTRP6. The immunogen is located within the last 50 amino acids of CTRP6.
CTRP6 antibody can be used for the detection of CTRP6 by Western blot at 1 and 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
CTRP6 Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
CTRP6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原
CTRP6 (C1QTNF6)
(Complement C1q Tumor Necrosis Factor-Related Protein 6 (C1QTNF6))
MGC148634 antibody, CTFP6 antibody, CTRP6 antibody, ZACRP6 antibody, 2810036M19Rik antibody, Ctrp6 antibody, C1q and TNF related 6 antibody, C1q and tumor necrosis factor related protein 6 antibody, C1QTNF6 antibody, C1qtnf6 antibody
背景
CTRP6 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP6 contains at least 4 glycosylation motifs, suggesting that CTRP6 may be highly post-translationally modified.