Anthrax Protective Antigen 抗体 (AA 300-350)
PA
适用: Bacillus anthracis
ELISA
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all Anthrax Protective Antigen (PA) products
- Anthrax Protective Antigen (PA)
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抗原表位
- AA 300-350
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适用
- Bacillus anthracis
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Anthrax Protective Antigen antibody is un-conjugated
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应用范围
- ELISA
- 纯化方法
- Anthrax PA Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Anthrax PA antibody was raised against a synthetic peptide corresponding to 16 amino acids in the middle of the Anthrax protective antigen protein. The immunogen is located within amino acids 300 - 350 of Anthrax PA .
- 亚型
- IgG
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anti-Anthrax Protective Antigen (PA) (Internal Region) antibody
PA 适用: Bacillus anthracis WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Anthrax PA antibody can be used for the detection of Anthrax PA protein in ELISA. It will detect 10 ng of free peptide at 1 μ,g/mL.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Anthrax PA Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- Anthrax PA antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- Anthrax Protective Antigen (PA)
- 别名
- Anthrax PA (PA 产品)
- 背景
- Anthrax PA Antibody: Anthrax infection is initiated by the inhalation, ingestion, or cutaneous contact with Bacillus anthracis endospores. B. anthracis produces three polypeptides that comprise the anthrax toxin: protective antigen (PA), lethal factor (LF), and edema factor (EF). PA binds to two related proteins on the cell surface, these are termed tumor epithelial marker 8 (TEM8)/anthrax toxin receptor (ATR) and capillary morphogenesis protein 2 (CMG2), although it is still unclear which is physiologically relevant. Following PA binding to its receptor, PA is cleaved into two fragments by a furin-like protease. The bound fragment binds both LF and EF, the resulting complex is then endocytosed which allows the translocation of LF and EF into the cytoplasm. These toxins are usually sufficient to cause rapid cell death, and often the death of the organism.
- 基因ID
- 3361714
- UniProt
- P13423
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