XAF1 抗体 (AA 230-280)
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- 抗原 See all XAF1 抗体
- XAF1 (XiAP Associated Factor 1 (XAF1))
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抗原表位
- AA 230-280
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This XAF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 纯化方法
- XAF-1 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- XAF-1 antibody was raised against a synthetic peptide corresponding to 16 amino acids near the middle of human XAF-1. The immunogen is located within amino acids 230 - 280 of XAF-1.
- 亚型
- IgG
- Top Product
- Discover our top product XAF1 Primary Antibody
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anti-XiAP Associated Factor 1 (XAF1) (AA 151-250) antibody
XAF1 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 1-301) antibodyXAF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 172-259) antibodyXAF1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 235-269), (C-Term) antibodyXAF1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB49525 unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 1-301) antibodyXAF1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 215-264) antibodyXAF1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 202-301) antibodyXAF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E5 unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 201-218) antibodyXAF1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 107-156) antibodyXAF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-XiAP Associated Factor 1 (XAF1) (C-Term) antibodyXAF1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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XAF-1 antibody can be used for the detection of XAF-1 by Western blot at 0.5 - 1 μ,g/mL. Multiple isoforms of XAF-1 exist and a doublet at ~30 kDa can be seen using anti-XAF-1 (IN). For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- XAF-1 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- XAF-1antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- XAF1 (XiAP Associated Factor 1 (XAF1))
- 别名
- XAF-1 (XAF1 产品)
- 别名
- BIRC4BP antibody, HSXIAPAF1 antibody, XIAPAF1 antibody, Fbxo39 antibody, XIAP associated factor 1 antibody, xaf1 antibody, XAF1 antibody, Xaf1 antibody
- 背景
- XAF-1 Antibody: XAF-1 binds to XIAP, an inhibitor of caspases-3, -7, and -9, and triggers its relocation from the cytosol to the nucleus. Overexpression of XAF-1 results in the neutralization of XIAP's ability to inhibit cell death. XAF-1 is normally expressed in all adult and fetal tissues but was found to be present in very low levels in a variety of cancer cell lines. In contrast, XIAP levels have been shown to be high in a majority of cell lines. Low XAF-1 and high basal expression of XIAP may therefore play a critical role in maintaining survival of cancer cell lines. Both IFN-alpha2 and IFN-beta can induce XAF-1 mRNA in all cells examined but induction of XAF-1 protein (as observed by immunoblot analysis) was seen only in cell lines sensitive to the apoptotic effects of IFNs.
- 分子量
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Predicted: 31, 33 kDa
Observed: 31 kDa - 基因ID
- 54739
- UniProt
- Q6GPH4
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