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ECSIT 抗体 (C-Term)

ECSIT 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990485
发货至: 中国
  • 抗原 See all ECSIT 抗体
    ECSIT
    抗原表位
    • 8
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 290-340, C-Term
    适用
    • 24
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 24
    • 2
    克隆类型
    • 24
    • 2
    多克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    This ECSIT antibody is un-conjugated
    应用范围
    • 24
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    ECSIT Antibody is Ion exchange chromatography purified.
    免疫原
    ECSIT antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human ECSIT. The immunogen is located within amino acids 290 - 340 of ECSIT.
    亚型
    IgG
    Top Product
    Discover our top product ECSIT Primary Antibody
  • 应用备注
    ECSIT antibody can be used for detection of ECSIT by Western blot at 0.5 to 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    ECSIT Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    ECSIT antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    ECSIT
    别名
    ECSIT (ECSIT 产品)
    别名
    CG10610 antibody, DmECSIT antibody, Dmel\\CG10610 antibody, dECSIT antibody, ECSIT antibody, Sitpec antibody, SITPEC antibody, CG10610 gene product from transcript CG10610-RA antibody, ECSIT signalling integrator antibody, ecsit antibody, ECSIT signalling integrator S homeolog antibody, ECSIT antibody, CpipJ_CPIJ003637 antibody, Ecsit antibody, ecsit.S antibody
    背景
    ECSIT Antibody: Activation of NF-κ,B as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses. Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 to kinases such as IRAK and other intermediates such as TNF receptor associated factor (TRAF)-6. ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway. Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis, indicating the possibility of cross-talk between the TLR/IL-B and Bmp signaling pathways.
    基因ID
    51295
    NCBI登录号
    NP_057665
    UniProt
    Q9BQ95
    途径
    TLR signaling, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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