CARD10 抗体 (N-Term)
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- 抗原 See all CARD10 抗体
- CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CARD10 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- CARMA3 antibody is human specific. At least three isoforms of CARMA3 are known to exist, this antibody will only detect isoform 1. CARMA3 antibody is predicted not to cross-react with other CARMA proteins.
- 纯化方法
- CARMA3 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- CARMA3 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CARMA3. The immunogen is located within the first 50 amino acids of CARMA3.
- 亚型
- IgG
- Top Product
- Discover our top product CARD10 Primary Antibody
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anti-Caspase Recruitment Domain Family, Member 10 (CARD10) (AA 863-1032) antibody
CARD10 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) (N-Term) antibodyCARD10 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) antibodyCARD10 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) (AA 341-600) antibodyCARD10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) (AA 481-530) antibodyCARD10 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) antibodyCARD10 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) (Internal Region) antibodyCARD10 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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CARMA3 antibody can be used for detection of CARMA3 by immunohistochemistry at 5 μ,g/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- CARMA3 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- CARMA3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))
- 别名
- CARMA3 (CARD10 产品)
- 别名
- CARD10 antibody, BIMP1 antibody, CARMA3 antibody, AI449026 antibody, Bimp1 antibody, Carma3 antibody, caspase recruitment domain family, member 10 antibody, caspase recruitment domain family member 10 antibody, Card10 antibody, CARD10 antibody
- 背景
- CARMA3 Antibody: CARMA proteins belong to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. As with CARMA1, the CARD domain of CARMA3 has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-κ,B activation. When expressed in cells, this protein binds to BCL10 and activates NF-κ,B Recent experiments have shown that CARMA3 is required for EGF-induced NF-κ,B activation and contributes to tumor growth in vivo, suggesting that CARMA3 may serve as a new therapeutic target for the treatment of EGFR-driven tumors.
- 基因ID
- 29775
- NCBI登录号
- NP_055365
- UniProt
- Q9BWT7
- 途径
- S100 Proteins
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