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NLRC4 抗体 (C-Term)

NLRC4 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990417
发货至: 中国
  • 抗原 See all NLRC4 抗体
    NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
    抗原表位
    • 9
    • 9
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 37
    • 15
    • 6
    • 2
    宿主
    • 26
    • 9
    • 2
    克隆类型
    • 27
    • 10
    多克隆
    标记
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NLRC4 antibody is un-conjugated
    应用范围
    • 27
    • 16
    • 10
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    纯化方法
    Ipaf Antibody is affinity chromatography purified via peptide column.
    免疫原
    Ipaf antibody was raised against a synthetic peptide corresponding to amino acids near the C-terminus of human Ipaf. The immunogen is located within the last 50 amino acids of Ipaf.
    亚型
    IgG
    Top Product
    Discover our top product NLRC4 Primary Antibody
  • 应用备注
    Ipaf polyclonal antibody can be used for the detection of Ipaf by Western blot at 1 and 2 μ,g/mL. A 110 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Ipaf Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    Ipaf antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
    别名
    Ipaf (NLRC4 产品)
    别名
    CARD12 antibody, CLAN antibody, CLAN1 antibody, CLANA antibody, CLANB antibody, CLANC antibody, CLAND antibody, CLR2.1 antibody, IPAF antibody, 9530011P19Rik antibody, Card12 antibody, NLR family CARD domain containing 4 antibody, NLR family, CARD domain containing 4 antibody, NLRC4 antibody, Nlrc4 antibody
    背景
    Ipaf Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adaptor molecules and proteases including several members of the caspase family. Another family of proteins that functions as a critical regulator of apoptosis and NFκ, signaling pathways is the CED-4/Apaf-1 (apoptosis protein activating factor-1) protein family. Ipaf (ICE protease activating factor) is a CED-4/Apaf-1 family member that activates caspase-1/ICE and can induce apoptosis in human cells in a caspase-1 dependent manner. Ipaf and caspase-1 are thought to interact with each other through the association of the Ipaf amino-terminal CARD (caspase recruitment domain) and amino-terminal CARD of caspase-1.
    分子量
    110 kDa
    基因ID
    58484
    NCBI登录号
    NP_067032
    UniProt
    Q9NPP4
    途径
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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