BCL2L13 抗体 (AA 280-330)
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- 抗原 See all BCL2L13 抗体
- BCL2L13 (BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13))
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抗原表位
- AA 280-330
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BCL2L13 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Bcl-rambo Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Bcl-rambo antibody was raised against a 15 amino acid synthetic peptide from near the center of human Bcl-rambo. The immunogen is located within amino acids 280 - 330 of Bcl-rambo.
- 亚型
- IgG
- Top Product
- Discover our top product BCL2L13 Primary Antibody
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anti-BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13) (AA 1-300) antibody
BCL2L13 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13) antibodyBCL2L13 适用: 人 WB, IP, ICC 宿主: 小鼠 Monoclonal Rocky-2 unconjugated
anti-BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13) (AA 1-485) antibodyBCL2L13 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13) (AA 395-444) antibodyBCL2L13 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13) (Intermediate Domain) antibodyBCL2L13 适用: 人, 小鼠, 大鼠 WB, EIA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13) (AA 342-369), (C-Term) antibodyBCL2L13 适用: 人 WB 宿主: 兔 Polyclonal RB16891 unconjugated
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- 应用备注
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Bcl-rambo antibody can be used for the detection of Bcl-rambo by Western blot at 2 and 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Bcl-rambo Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- Bcl-rambo antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- BCL2L13 (BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13))
- 别名
- Bcl-rambo (BCL2L13 产品)
- 别名
- si:ch211-238n5.7 antibody, Mil1 antibody, BCL-RAMBO antibody, Bcl2-L-13 antibody, MIL1 antibody, E430016C20Rik antibody, Mil-1 antibody, BCL2 like 13 antibody, BCL2-like 13 (apoptosis facilitator) antibody, BCL2L13 antibody, bcl2l13 antibody, Bcl2l13 antibody
- 背景
- Bcl-rambo Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains. A novel, widely expressed member termed Bcl-rambo was recently identified. This protein is localized to mitochondria in mammalian cells and its overexpression induces apoptosis which could be blocked by co-expression of inhibitor of apoptosis proteins (IAPs) such as XIAP, cIAP1, and cIAP2. Bcl-rambo shows overall homology to the anti-apoptotic members containing BH motifs, but unlike Bcl-2, the C-terminal membrane anchor of Bcl-rambo is preceded by a unique 250 amino acid insertion. This region by itself can induce apoptosis more efficiently than the Bcl-2 homology regions, suggesting that Bcl-rambo may be important other pro-apoptotic pathways.
- 基因ID
- 23786
- UniProt
- Q9BXK5
- 途径
- Positive Regulation of Endopeptidase Activity
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