FLASH 抗体 (C-Term)
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- 抗原 See all FLASH (CASP8AP2) 抗体
- FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FLASH antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 纯化方法
- FLASH Antibody is affinity chromatography purified via peptide column.
- 免疫原
- FLASH antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human FLASH which differ from those of mouse by one amino acid. The immunogen is located within the last 50 amino acids of FLASH.
- 亚型
- IgG
- Top Product
- Discover our top product CASP8AP2 Primary Antibody
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anti-CASP8 Associated Protein 2 (CASP8AP2) antibody
CASP8AP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CASP8 Associated Protein 2 (CASP8AP2) (AA 110-159) antibodyCASP8AP2 适用: 人, 小鼠, 大鼠, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-CASP8 Associated Protein 2 (CASP8AP2) (AA 1733-1982) antibodyCASP8AP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CASP8 Associated Protein 2 (CASP8AP2) (N-Term) antibodyCASP8AP2 适用: 人, 小鼠, 大鼠, 犬, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-CASP8 Associated Protein 2 (CASP8AP2) (N-Term) antibodyCASP8AP2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-CASP8 Associated Protein 2 (CASP8AP2) (C-Term) antibodyCASP8AP2 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-CASP8 Associated Protein 2 (CASP8AP2) antibodyCASP8AP2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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FLASH antibody can be used for detection of FLASH by Western blot at 0.5 μ,g/mL. An approximate 220 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- FLASH Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- FLASH antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
- 别名
- FLASH (CASP8AP2 产品)
- 别名
- CASP8AP2 antibody, FLASH antibody, fc74h10 antibody, wu:fc74h10 antibody, zgc:113449 antibody, CED-4 antibody, RIP25 antibody, AA387232 antibody, D4Ertd659e antibody, mKIAA1315 antibody, caspase 8 associated protein 2 antibody, CASP8AP2 antibody, casp8ap2 antibody, Casp8ap2 antibody
- 背景
- FLASH Antibody: A novel mammalian CED-4 homologous was recently identified and cloned in mouse and human and designated FLASH (for FLICE-associated huge protein). FLASH is involved in Fas induced apoptosis. It is recruited to Fas after the receptor cross-linking. Overexpression of wild type of FLASH facilitates and its dominant negative form inhibits Fas induced apoptosis. FLASH interacts with the DEDs of caspase-8 and FADD through the DED-like domain of FLASH and mediates activation of caspase-8. There are parallels between FLASH and Apaf-1/CED-4 although there are arguments against their structural similarity. FLASH is widely expressed.
- 分子量
- 220 kDa
- 基因ID
- 9994
- UniProt
- Q9UKL3
- 途径
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
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