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MPRIP 抗体 (C-Term)

MPRIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990325
发货至: 中国
  • 抗原 See all MPRIP 抗体
    MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))
    抗原表位
    • 8
    • 7
    • 7
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 38
    • 30
    • 29
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 46
    • 1
    克隆类型
    • 46
    • 1
    多克隆
    标记
    • 17
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    This MPRIP antibody is un-conjugated
    应用范围
    • 14
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    RIP3 Antibody is affinity chromatography purified via peptide column.
    免疫原
    Anti-RIP3 antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of murine RIP3. The immunogen is located within the last 50 amino acids of RIP3.
    亚型
    IgG
    Top Product
    Discover our top product MPRIP Primary Antibody
  • 应用备注
    WB: 0.1-0.5 μ,g/mL, IHC-P: 5 μ,g/mL, IF: 20 μ,g/mL, IP: 20 μ,g/mL.

    Antibody validated: Western Blot in mouse and human samples, Immunohistochemistry in mouse and rat samples, Immunofluorescence in mouse and rat samples, Immunoprecipitation in human samples, Immunogold EM in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    RIP3 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    RIP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Wu, Chung, Cao, Jin, Edmiston, Hickman, Levy, Whalen, Abrams, Degterev, Lo, Tozzi, Kaplan, El Khoury, Whalen: "Genetic inhibition of RIPK3 ameliorates functional outcome in controlled cortical impact independent of necroptosis." in: Cell death & disease, Vol. 12, Issue 11, pp. 1064, (2021) (PubMed).

  • 抗原
    MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))
    别名
    RIP3 (MPRIP 产品)
    别名
    M-RIP antibody, MRIP antibody, RHOIP3 antibody, RIP3 antibody, p116Rip antibody, 9530046C02 antibody, AA536749 antibody, AI647711 antibody, C76423 antibody, Rhoip3 antibody, mKIAA0864 antibody, M-rip antibody, Mrip antibody, myosin phosphatase Rho interacting protein antibody, MPRIP antibody, Mprip antibody
    背景
    RIP3 Antibody: Certain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis. Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3. RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, mediates TNFR1 induced apoptosis, and attenuates RIP and TNFR1 induced NF-κ,B activation. Overexpression of RIP3 induces apoptosis and NF-κ,B activation. The messenger RNA of RIP3 is expressed in a subset of adult tissues.
    分子量
    Predicted: 53kD for mouse RIP3 and 57kD for human RIP3

    Observed: 53kD for mouse RIP3 and 57kD for human RIP3 kDa
    基因ID
    56532
    UniProt
    Q9QZL0
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