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RIPK2 抗体 (N-Term)

RIPK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990281
发货至: 中国
  • 抗原 See all RIPK2 抗体
    RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
    抗原表位
    • 12
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 67
    • 36
    • 18
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 63
    • 6
    克隆类型
    • 65
    • 4
    多克隆
    标记
    • 39
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RIPK2 antibody is un-conjugated
    应用范围
    • 52
    • 33
    • 25
    • 9
    • 9
    • 7
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    纯化方法
    RICK Antibody is affinity chromatography purified via peptide column.
    免疫原
    RICK antibody was raised against a peptide corresponding to 20 amino acids near the amino terminus of human RICK. The immunogen is located within the first 50 amino acids of RICK.
    亚型
    IgG
    Top Product
    Discover our top product RIPK2 Primary Antibody
  • 应用备注
    RICK antibody can be used for detection of RICK by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human and mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    RICK Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    RICK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
    别名
    RICK (RIPK2 产品)
    别名
    RIPK2 antibody, 2210420D18Rik antibody, CARD3 antibody, CARDIAK antibody, CCK antibody, D4Bwg0615e antibody, RICK antibody, RIP2 antibody, GIG30 antibody, receptor interacting serine/threonine kinase 2 antibody, receptor (TNFRSF)-interacting serine-threonine kinase 2 antibody, receptor-interacting serine-threonine kinase 2 antibody, RIPK2 antibody, Ripk2 antibody
    背景
    RICK Antibody: Apoptosis is mediated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. DD-containing serine/threonine kinase RIP regulates Fas-induced apoptosis. A novel CARD-containing serine/threonine kinase was recently identified and designated RICK/RIP2/CARDIAK for RIP-like interacting CLARP kinase, receptor interacting protein-2, and CARD-containing ICE associated kinase, respectively. RICK contains an N-terminal kinase catalytic domain and a C-terminal CARD domain. Overexpression of RICK induced apoptosis and activation of NF-κ,B and JNK. RICK interacts with members of the TRAF family, CLARP and caspase-1. Thus, RICK represents a novel kinase that regulates TNF and Fas induced-apoptosis and that is involved in the generation of proinflammatory cytokine IL-1β,. The messenger RNA of RICK is expressed in multiple human tissues.
    分子量
    Predicted: 59 kDa

    Observed: 59 kDa
    基因ID
    8767
    UniProt
    O43353
    途径
    TCR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades
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